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Measurement Uncertainty for Analysis of Volatile Organic Compound in Cigarette Mainstream Smoke  

Ka, Mi-Hyun (KT&G Central Research Institute)
Cho, Sung-Eel (KT&G Central Research Institute)
Kim, Mi-Ju (KT&G Central Research Institute)
Lee, Chul-Hee (KT&G Central Research Institute)
Ji, Sang-Un (KT&G Central Research Institute)
Jeong, Jong-Soo (KT&G Central Research Institute)
Kim, Yong-Ha (KT&G Central Research Institute)
Min, Young-Keun (KT&G Central Research Institute)
Publication Information
Journal of the Korean Society of Tobacco Science / v.28, no.2, 2006 , pp. 144-151 More about this Journal
Abstract
A measurement uncertainty for analysis of volatile organic compound (benzene) in cigarette mainstream smoke was carried out. In this study one point re-calibration method was used to estimate uncertainty for benzene. The measurement uncertainty was calculated based on the uncertainty sources of each analysis step, quality appraisal sources, drift and repeatability. As a result, the concentration and expanded uncertainty of benzene in cigarette mainstream smoke were measured as $38.08{\pm}4.36{\mu}g/cig$. Relative uncertainty of drift and repeatability obtained were 5% and 3%, respectively.
Keywords
uncertainty; one-point re-calibration method; benzene; drift; repeatability;
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1 Brunnemann K. D., Kagan M. R., Cox J. E. and Hoffman D. (1989) Determination of benzene, toluene and 1,3-butadiene in cigarette smoke by GC-MSD. Experimental Pathology 37: 108-113   DOI
2 Brunnemann K. D., Kagan M. R., Cox J. E. and Hoffman D. (1990) Analysis of 1,3-butadiene and other selected gas-phase components in cigarette mainstream and sidestream smoke by gas chromatography-mass selective detection. Carcinogenesis 11: 1863-1868   DOI   ScienceOn
3 C. J. SMITH, S. D. LIVINGSTON and D. J. DOOLITTLE. (1997) An International Literature Survey of 'IARC Group I Carcinogens' Reported in Mainstream Cigarette Smoke. Food and Chemical Toxicology 35: 1107-1130   DOI   ScienceOn
4 Motohiko Muramatsu., Shozo Isono. and Tsuyoshi Sasa. (2001) Estimation of Uncertainties of Water and Nicotine Measurements in TPM with Gas Chromatography. Presented at the 9th ACS Meeting in Bali
5 Woo J. C. (2000) Uncertainty in Mesurements and Analysis(I). Anal. Sci. & Tech. 13(2): 19A-26A
6 IARC (1995) Monographs on the Evaluation of Carcinogenic Risk to Humans. vol. 1-60. Lyon, France
7 CORESTA Recommended Method No 23. (1989) Determination of total and Nicotine-free Dry Particulate Matter using a routine Analytical cigarette smoking machine determination of total Particulate matter and preparation for water and Nicotine measurements
8 ISO (1993) BIPM, IEC, IFCC, ISO, IUPAC, IUPAP, OIML, International Vocabulary of basic and general terms in Metrology
9 Peter Gans., Hohn Wiley & Sons. (1992) Data fitting in the Chemical Sciences by the Method of Least Squares. Toronto
10 Heo S. C., Min J. S., Park J. S., Lim M. A. and Park S. W. (2004) Method Validation and Uncertainty Estimation for Toluene Measurement in Biological Fluid by HS-GC. Anal. Sci. & Tech. 17(6): 443-453
11 UK Arista Recommend Method. (2003) Determination of Volatile Organic Compounds Yields in Cigarette Smoke. Tobacco Manufactures Association
12 Kim Y. D., Woo J. C., Oh S. H., Kim B. M., Bae H. K. and Kim K. S. (2005) Measurement uncertainty for QC/QA applied to the chemical analysis. Anal. Sci. & Tech. 18(6): 475-482
13 Trevor J. Farrant., LGC. and Teddition. (1997) Practical Statistics for analytical Scientist. UK