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http://dx.doi.org/10.14775/ksmpe.2019.18.7.071

Measurement of Substance Diffusion on a Bio-body Surface Using Laser Plasma Spectroscopy  

Yoon, Sangwoo (Department of Mechanical & Automotive Engineering, Seoul National University of Science & Technology)
Oh, Jiheon (Department of Mechanical & Automotive Engineering, Seoul National University of Science & Technology)
Park, Seongyong (Department of Mechanical & Automotive Engineering, Seoul National University of Science & Technology)
Jung, Jaekyeong (Department of Mechanical & Automotive Engineering, Seoul National University of Science & Technology)
Kim, Joohan (Department of Mechanical & Automotive Engineering, Seoul National University of Science & Technology)
Publication Information
Journal of the Korean Society of Manufacturing Process Engineers / v.18, no.7, 2019 , pp. 71-76 More about this Journal
Abstract
The diffusion of the drug component of the inflammatory patch into the living tissue was analyzed by laser induced plasma spectroscopy (LIBS). Calcium element, which is a diffusion catalyst of the drug in the inflammatory analgesic patch, is transferred into the body through the diffusion process of the substance. The test pieces used in the experiment are pig skin tissues which are similar to human skin. As a result, the diffusion coefficient D of the calcium element was found to be average $8.24{\times}10^{-2}({\mu}m^2/s)$. Experimental results showed that the most influential factors on the diffusion of materials were temperature variables.
Keywords
LIBS; Medicated-patch; Diffusion coefficient; Pig skin;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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