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http://dx.doi.org/10.15433/ksmb.2014.6.2.053

Effect of Antimicrobial Activity of the Glutaraldehyde Cross-linked Glucosamine  

Lee, Choon Geun (Department of Biomedical Science, College of Bio-nano, Gachon University)
Hwang, You Jin (Department of Life Science, College of Bio-nano, Gachon University)
Park, Jae Kweon (Department of Life Science, College of Bio-nano, Gachon University)
Publication Information
Journal of Marine Bioscience and Biotechnology / v.6, no.2, 2014 , pp. 53-61 More about this Journal
Abstract
This study was investigated the antimicrobial activity of glutaraldehyde cross-linked glucosamine. Glutaraldehyde was used as a cross-linker which specifically combines an amine-group of molecules. To optimize the mixing ratio of glutaraldehyde and glucosamine, mixing ratio was set up 1:1, 2:1, 3:1 and 0.5:1 in molarity, respectively. The optimum mixing ratio of glucosamine and glutaraldehyde was found to be 3:1 using thin layer chromatography based on the production of complex. Glucosamine-glutaraldehyde cross-linked complex (Ggcc) revealed significant antimicrobial activity toward PWG than F1, both microbial strains were isolated from porcine semen as antibiotics resistance bacteria (ARB). These results clearly demonstrate that Ggcc has potential bactericidal activity toward ARB in porcine semen.
Keywords
Glucosamine; Glutaraldehyde; Cross-linked; Antimicrobial activity; Porcine semen;
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