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Anti-microbial, Anti-inflammatory and Anti-oxidative Effects of Herbal Medicine Extracts as Anti-gingivitis Ingredients  

Lee, Dong-Jae (Aekyung Central Research Laboratories Personal-care Products Part)
Han, Il-Min (Aekyung Central Research Laboratories Personal-care Products Part)
Kim, Woo-Jung (Aekyung Central Research Laboratories Personal-care Products Part)
Cho, In-Sik (Aekyung Central Research Laboratories Personal-care Products Part)
Publication Information
Journal of dental hygiene science / v.10, no.1, 2010 , pp. 25-29 More about this Journal
Abstract
This study was to estimate the effect of herbal medicines on periodontal disease. To screen effective materials for periodontal disease, we performed a series of test for 15 herbal medicine extracts. MIC test for P. gingivalis, IL-$1{\alpha}$ inhibition test, MMP-1 inhibition test and SOD activation test were carried out for herbal medicine extracts, respectively. The results are as followings : 1) Eunhang, Youkdoogu, Daewhang, Hoobak, Goojulcho, Yongacho, Mokhyang, Sesin, Sancho and Hoehyang extracts were effective for reduce P. gingivalis, 2) Eunhang, Jacyak, Youkdoogu, Hagocho, Hoobak, Guaru and Sanyak extracts showed high IL-$1{\alpha}$ inhibition rates, 3) Eunhang and Youkdoogu extracts have effects on MMP-1 inhibition, 4) Eunhang, Sanyak and Youkdoogu extracts effectively activate SOD. Especially, Eunhang extract has high performance through all estimations and can effectively prevent and treat periodontal disease.
Keywords
P. gigivalis; MIC; IL-$1{\alpha}$; MMP-1; SOD; Eunhang(leaf) extract;
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