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http://dx.doi.org/10.7231/jon.2015.26.4.383

Herbal Medicine for Tension-type Headache: Systematic Review and Meta Analysis of Randomized Controlled Trials  

Choi, Eun-Ji (Department of Neuropsychiatry, College of Korean Medicine, KyungHee University)
Kwon, Chan-Young (Department of Neuropsychiatry, College of Korean Medicine, KyungHee University)
Han, Kyung-Hun (Department of Counseling Psychology, HanYang Cyber University)
Kim, Jong-Woo (Department of Neuropsychiatry, College of Korean Medicine, KyungHee University)
Chung, Sun-Young (Department of Neuropsychiatry, College of Korean Medicine, KyungHee University)
Publication Information
Journal of Oriental Neuropsychiatry / v.26, no.4, 2015 , pp. 383-406 More about this Journal
Abstract
Objectives: People with tension-type headache generally take pain relievers, but long term dependency causes problems as well as side effects. The present study aimed to provide clinical evidence of herbal medicine for tension-type headache by systematic review of randomized controlled trials on the effect of herbal medicine for tension-type headache. Methods: Randomized or quasi-randomized controlled trials that verified effects of herbal medicine intervention on patients with tension-type headache were included in the study. A literature search of English, Japanese, Chinese, Korean databases was performed. The selected literature were assessed by Jadad scale and Risk of Bias. Results: Herein, 40 reports were selected from a total of 157. Meta-analyses of 2 trials indicated that the effective rate was significantly higher in the herbal medicine treatment group, as compared to the placebo control (risk ratio: 1.49, 95% confidence interval (CI): 1.23 to 1.80, p<0.0001, I2=0%). Four trials that compared herbal medicine with routine care with routine care only group showed a significantly higher effective rate of benefits for herbal medicine with routine care, as compared to routine care only (RR: 1.57, 95% CI: 1.18 to 2.10, p=0.002, I2=0%). Conclusions: The effective rate was significantly higher than control and adverse events were less in the treatment group. Pattern analysis (辨證) indicated that the studies on wind-fire pattern (風火證) were highest. Yougeun-bang (柔筋方) in prescription and Paeoniae Radix Alba (白芍藥) in medicinal herbs were most used. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance.
Keywords
Tension-type headache; Herbal medicine; Randomized controlled trial; Meta-analysis; Systematic review;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Wang ZW. Study on optimization of treatment program for tension-type headache based on liver. Bejing University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2011. (the title was translated from 神经性頭痛从肝调治诊疗方案的优选研究)
2 Bai YB. Clinical study of regulating the stagnation of liver qi and activating blood for chronic tension-type headache. Medical Innovation of China 2011. (the title was translated from 调肝解郁理氣活血治疗慢性紧张性頭痛临床研究)
3 Fan CF, Qian LF. Clinical study of soothing the liver and nourishing the blood and emolliating the liver for tension-type headache. Modern Journal of Integrated Traditional Chinese and Western Medicine 2011. (the title was translated from 疏肝解郁, 养血柔肝法治疗紧张性頭痛疗效观察)
4 Wang LY. Clinical study of Bojangdootongnyeong-capsule for tension-type headache. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease 2011. (the title was translated from 步长頭痛宁胶囊治疗紧张型頭痛的远期疗效观察)
5 Wang CX. Research on Traditional Chinese Medicine Combined Therapy of Chronic Tension-Type Headache of Feng-yu Type. Shandong University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2011.
6 Dou YX. Clinical Research on Self-Made Qingyuhuatan Particles in Treating Ischemic Stroke in Convalescent Stage (Phlegm and Blood Stasis Mutual Resistance Type). Zhangchun University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2012.
7 Fang WJ, Zhao Y. Clinical study of modified Danchisoyo-san for tension-type headache. Clinical Journal of Traditional Chinese Medicine 2013; (the title was translated from 丹栀逍遥散加减治疗紧张型頭痛疗效观察)
8 Yang XY, Guo ZS, Lai YW, Chen X, Liu JX, Kuang J, Huang QY. Clinical study of Gontae capsule combined with Flupentixol melitracen for tension-type headache. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2013. (the title was translated from 坤泰胶囊联合氟哌噻吨美利曲辛治疗紧张型頭痛临床研究)
9 Pan WJ. 105 cases of integrative medicine for tensiontype headache. Journal of Emergency in Traditional Chinese Medicine. 2013. (the title was translated from 中西医结合治疗紧张型頭痛105 例)
10 Chen ZF. 38 cases of liver-pacifying and tonifying kidney combined with pillow treatment for climacteric tension-type headache. Yunnan Journal of Traditional Chinese Medicine and Materia Medica 2012. (the title was translated from 平肝补肾法结合药枕治疗更年期紧张型頭痛３８例)
11 Zhang SQ, Wang CX, Han H, Xu XY, Wang XL, Guo YL. Clinical study of comprehensive treatmnet for chronic tension-type headache with wind-fire pattern. Journal of Shandong University of Traditional Chinese Medicine 2012. (the title was translated from 综合方案治疗慢性紧张型頭痛風火證疗效分析)
12 Zhang SQ, Wang CX, Han H, Xu XY, Wang XL, Guo YL. Clinical study of comprehensive treatment in traditional Chinese medicine for chronic tension-type headache with qi and blood deficiency pattern. Guangming Journal of Chinese Medicine (the title was translated from 慢性紧张型頭痛氣血亏虛證中医综合治疗方案疗效评价)
13 Li LL. Clinical Research on Tension-type Headache Treated with Shengjiang Powder and Sini Powder. Guangzhou University of Traditional Chinese Meidicine, Master's thesis of Traditional Chinese Medicine. 2013.
14 Jia WF. A Clinical Observation on Treating Tension-Type Headache by the Combinaion of Acupuncture and Zhengtianwan Pill. Heirongjiang University of Traditional Chinese Medicine, Master's thesis of Traditional Chinese Medicine. 2013.
15 Wang ZS, Zhao XC, Wang KM, shi J. Clinical Curative Effect of Twenty Five-ingredient Coral Pill on Tension Headache. Research of Integrated Traditional Chinese and Western Medicine 2013.
16 Zhai HF, Wang M, ang Xue. 45 cases of combined therapy of acupuncture and Chinese herbal medicine for tension-type headache. Chinese Medicine Modern Distance Education of China 2014. (the title was translated from 针药并用治疗紧张型頭痛45例)
17 Zhang P. The Clinical Observation of Flavored Siwu De Coction for the Treatment of Chronic Tension-Type Headache. Heirong University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2014.
18 Zhao YC, Jin L, Cheng YS. Clinical study on efficacy and safety of Chinese herbal medicine for tension-type headache. Chinese Archives of Traditional Chinese Medicine 2015. (the title was translated from 自拟中药汤剂联合西药治疗紧张型頭痛疗效分析及不良反应观察)
19 Shi YH. 45 cases of combined therapy of acupuncture, moxibustion and Chinese herbal medicine for tension-type headache. Nei Mongol Journal of Traditional Chinese Medicine 2014. (the title was translated from 针灸配合中药治疗紧张性頭痛45例)
20 Sheng YJ. Clinical Research of Jieyu Analgesic Decoction in Treating Tension-type Headache with Depression. Shandong University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2014.
21 Peng L. Clinical study of Chinese herbal medicine for tension-type headache. For all Health (the title was translated from 中医药治疗紧张型頭痛效果观察)
22 Guo YL. Clinical study on effect of comprehensive therapy of traditional Chinese medicine for quality of life with chronic tension-type headache with blood deficiency pattern. World Chinese Medicine. (the title was translated from 中医综合治疗方案干预慢性紧张型頭痛氣血亏虛證生存质量临床研究)
23 Guo SM. 40 cases of acupuncture and Sigalhaegi-tang for tension-type headache. Chinese Medicine Modern Distance Education of China. 2015. (the title was translated from 针刺联合柴葛解肌汤治疗紧张性頭痛40 例)
24 Xu JP. 40 cases of Pyeongganhwaryul-tang for tension-type headache. Guangming Journal of Chinese Medicine. 2015. (the title was translated from 中药平肝活血汤治疗紧张型頭痛40 例)
25 Zhao YC, Cheng YS, Wang PL, Jin L. Clinical study on efficacy and safety of integrative medicine for tension-tyep headache. Chinese Archives of Traditional Chinese Medicine. 2015. (the title was translated from 中西医结合治疗紧张型頭痛临床疗效分析及安全性评价)
26 The Textbook Compilation Committee of Neuropsychiatry of oriental medical schools in nation. The Neuropsy chiatry of Oriental Meidicne, Revised ed. Seoul:Jipmoondang. 2006:156-61.
27 Lee KS. The study about oriental medical diagnosis and approach related to weighting according to differentiation of CTTH. Daejeon University, Master's thesis of Traditional Korean Medicine. 2010.
28 Kwon KM, Kim KL, Shin YL, Park SY, Park DI. A Clinical Study of One Hundred Twenty Patients Admitted with Headache. Korean journal of acupuncture 2012;29(4):643-61.
29 The Textbook Compilation Committee of Internal Medicine of Heart of oriental medical schools in nation. The Internal Medicine of Heart of Oriental Meidicne, 4th ed. Seoul:Goonja Publishment. 2006:299-316.
30 Park YH. A Study of oriental-western medical research in tension headache. Journal of oriental neuropsychiatry 2004;15(1):1-7.
31 Lee KS, Kim MJ, Park MR, Lee SB, Hong KY. The study about oriental medical diagnosis and approach related to weighting according to differentiation of CTTH. The Journal of Korean Medicine 2010;31(5): 41-59.
32 Park KW. The role of antidepressants and antipsychotic drugs in treating headache. Korean Journal of Headache 2005;6(1):34-9.
33 Lee KS. Kim MJ, Park MR, Lee SB, Hong KY. The study about oriental medical diagnosis and approach related to weighting according to differentiation of CTTH. The Journal of Korean Medicine 2010;31(5):41- 59.
34 Manchikanti L, Ailinani H, Koyyalagunta D, Datta S, Singh V, Eriator I, et al. A systematic review of randomized trials of long-term opioid management for chronic non-cancer pain. Pain Physician 2011;14:91-121.
35 Luedtke K, Allers A, Schulte LH, May A. Efficacy of nterventions used by physiotherapists for patients with headacheand migraine-systematic review and meta-analysis. Cephalalgia 2015.
36 Wing-Fai Yeung, Ka-Fai Chung, Ka-Yan Ng, Yee-Man Yu, Eric Tat-Chi Ziea, Bacon Fung-Leung Ng. A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression. Journal of Psychiatric Research 2014;165-75.
37 This paragraph was cited from Mhun KH, Chun YH, Hong JP, Auh QS. Evaluation of Temporomandibular Disorders with Tension-Type Headache by Age. Journal of Oral Medicine and Pain 2009;34(1):103-14.
38 Redillas C. Solomon S. Prophylactic pharmacologicaltreatmnet of chronic daily headache. Headache 2000;40:83-102.   DOI
39 Kwon KM, Kim KL, Shin YL, Park SY,Park DI. A Clinical Study of One Hundred Twenty PatientsAdmitted with Headache. Korean journal of acupuncture2012;29(4):643-61.
40 Yoon JW, Moon DE, Yang SY, Park CM. Therapeutic effectof the patients with chronic migraine in pain clinic. KoreanJ Pain. 2004;17:146-52.   DOI
41 Mesa-Jiménez JA, Lozano-López C, Angulo-Díaz-Parreño S, Rodríguez-Fernández ÁL, De-la-Hoz-Aizpurua JL, Fernández-de-Las-Peñas C. Multimodal manual therapy vs. pharmacological care for management of tension type headache: A meta-analysis of randomized trials. Cephalalgia 2015;35(14):1323-32.   DOI
42 Kim SY, Park JE, Seo HJ, Lee YJ, Jang HB, Son HJ, Shin CM. NECA’s guidance for undertaking systematic reviews and meta-analyses for intervention. National Evidence-based Healthcare Collaborating Agency, 2011;64.
43 Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12   DOI
44 Shi HF. Clinical Observation of “Headache Decoction” & Relaxation Therapy in Treating Tension Headache. Shanghai Journal of Traditional Chinese Medicine 2006.
45 Jadad AR, Moore RA, Carroll D, Jenkinson C, ReynoldsDJ, Gavaghan DJ, McQuay HJ. Assessing the quality ofreports of randomized clinical trials: is blinding necessary?Control Clin Trials 1996;17:1-12.   DOI
46 LimSM, Shin IS, Lee SH, Seo KH, Jeong YM, Jang JE. Toolsfor assessing quality and risk of bias by levels ofevidence. J Korean Med Assoc 2011;54(4): 419-29.   DOI
47 Kim SY, Park JE, Seo HJ, Lee YJ, Jang HB, Son HJ, Shin CM. NECA’s guidance for undertaking systematic reviews and meta-analyses for intervention. National Evidence-based Healthcare Collaborating Agency, 2011;66.
48 Ciytan headache research group. 114 cases of Chinese medicine for headache. Guide of China Medicine 2007;149-50. (the title was translated from 中药治疗頭痛114例临床研究)
49 Liu YH, Pan GQ. 30 cases of Sihosogan-san for tensiontype heaeache. Guiding Journal of Traditional Chinese Medicine and Pharmacy 2008. (the title was translated from 柴胡疏肝 散加减治疗紧张性頭痛30例小结)
50 Chen YW. Clinical study of integrative medicine for tension-type headache. Journal of Liaoning University of Traditional Chinese Medicine 2009. (the title was translatedfrom 中西医结合治疗紧张性頭痛疗效观察)
51 Li CJ, Zhang QR. Clinical study of integrative medicine for tension-type headache. Chinese Traditional and Herbal Drugs 2008. (the title was translated from 中西医结合治疗紧张性頭痛疗效观察)
52 Lee HY. Efficacy and satety of Cheongsangkyuntong-tang for chronic tension-type headache: Randomized, double-blind, placebo-controlled study. Daejeon University, Doctor's thesis of Traditional Korean Medicine. 2009.
53 Jin FH. Clinical study of treating for releasing the liver qi depression for tension-type headache. Jilin Medical Journal 2010. (the title was translated from 调肝解郁治疗 慢性紧张性頭痛临床研究)
54 Dai J. Clinical Observation of the 25 Wei Coral Pill Treatment Efficacy for Tension Headache. Hebei University of Traditional Chinese Medicine, Master's thesis of Clinical integrative medicne. 2010.
55 He PJ. Clinical Study on Tension-type Headache Treated with Removing Heat from the Liver Following Traditional Chinese Medicine. 中国中医科学院 硕士 2009.
56 Huang ZL. Clinical study of Yanghyeolchengnue-granule for tension-type headache of college student. Chinese Journal of School Doctor 2009. (the title was translated from 养血清脑颗粒治疗大学生紧张性頭痛的效果观察)
57 Ran GS. The Clinical Study of the Treatment of Shugan Jieyu Kaiqiao on Tension-type Headache. Hebei University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicne. 2010.
58 Wang XB. Clinical Study on Tension-type Headache Treated with Dispelling Stasis, Resolving Phlegm and Soothing the Liver Following Traditional Chinese Medicine. Shandong University of Traditional Chinese Medicine, Master's thesis of Chinese internal medicine. 2010.
59 Zou LH. Clinical study of Mangin-tang for chronic tension-type headache. Clinical Journal of Traditional Chinese Medicine 2010. (the title was translated from 自拟慢紧汤治疗慢性紧张性頭痛疗效观察)
60 Xu H. Clinical Study on Effect of Jiaweitoutongxinyihao Decoction in Treating Tension-Type Headache (Wind-Damp Headache). Nanfang University of Medicine, Master's thesis of intergrative medicine of clinical internal medicine.2010.
61 Hu ZQ, Wu HY, Hou SW. Clinical study of comprehensive therapy in traditional Chinese medicine for chronic tension-type headache with wind-phlegm pattern. Journal of Shandong University of Traditional Chinese Medicine, (the title was translated from 慢性紧张型頭痛風痰證中医综合治疗方案疗效评价)