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Immuno stimulatory activities of Samul-tang, Sagunja-tang, Pamul-tang and Sipjeondaebo-tang in vitro  

Lee, Ho-Young (Herbal EBM reserach center. Korea Institute of Oriental Medicine)
Ha, Hye-Kyung (Herbal EBM reserach center. Korea Institute of Oriental Medicine)
Jung, Da-Young (Herbal EBM reserach center. Korea Institute of Oriental Medicine)
Lee, Nam-Hun (Herbal EBM reserach center. Korea Institute of Oriental Medicine)
Shin, Hyeun-Kyoo (Herbal EBM reserach center. Korea Institute of Oriental Medicine)
Publication Information
Journal of Oriental Neuropsychiatry / v.21, no.4, 2010 , pp. 41-51 More about this Journal
Abstract
Objectives : Samul-tang(SM). Sagunja-tang(SG). Pamul-tang(PM) and Sipjeondaebo-tang(SJ) was used many diseases such as sterility. menstrual disorder. general prostration. recruitment in Korea. We investigated the immune stimulatory activities of SG. SM. PM and SJ in in vitro. Methods: For comparision for effective of SM. SG. PM and SJ. this study examined anti-inflammation(NO. PGE2 assay). anti-oxidation(DPPH assay) and immune response in in vitro assay. For immune response activities. this study used NO synthesis on RAW 264.7 cells, splenocyte proliferation and cytokine assay(IL-2, IL-4) in splenocyte. Results: The results showed that SG. SM. PM and SJ were no significant effect anti-oxidation and anti-inflammatory effects. For immune response. they showed the splenocyte proliferation and macrophage proliferation. We confirmed that they synthesised NO a dose-dependent manner significantly and secreted the IL-4. Conclusions : These results suggested the SG, SM, PM and SJ had immune stimulatory activity. A efficacy of immune response in them had produced similar results.
Keywords
Samul-tang; Sagunja-tang; Pamul-tang; Sipjeondaebo-tang; Immune stimulatory activity;
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Times Cited By KSCI : 8  (Citation Analysis)
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