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http://dx.doi.org/10.5090/kjtcs.2010.43.6.694

The Utility of Scalene Lymph Node Biopsy in the Diagnosis of Sarcoidosis  

Chung, Won-Sang (Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital, College of Medicine, Hanyang University)
Kim, Young-Hak (Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital, College of Medicine, Hanyang University)
Song, Young-Joo (Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital, College of Medicine, Hanyang University)
Kim, Ji-Hoon (Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital, College of Medicine, Hanyang University)
Kim, Hyuck (Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital, College of Medicine, Hanyang University)
Publication Information
Journal of Chest Surgery / v.43, no.6, 2010 , pp. 694-699 More about this Journal
Abstract
Background: In addition to clinical and radiographic findings, a histopathologic examination is important in the diagnosis of sarcoidosis. This study evaluated the diagnostic usefulness of a scalene node biopsy in patients with suspected sarcoidosis. Material and Method: We studied 35 patients who underwent scalene node biopsy because of suspicion of sarcoidosis on a chest x-ray and a computerized tomogram between 2001 and 2009, regardless of symptoms. Result We studied 15 men and 20 women whose mean age was $41.51{\pm}11.21$ years (25~64). Three among the 35 were diagnosed with tuberculosis and 27 with sarcoidosis, resulting in a diagnostic yield of 84.4%. The mean lymph node diameter size was 1.3 (${\pm}0.12$) (0.3~3.6 cm) cm. We divided the group of participants according to stage - whether on chest x-ray the lung was affected or not (stage 0, 1 and stage 2, 3). We divided lymph node sizes as well - whether they were larger than 1 cm or smaller than 1 cm. For these subgroups, there were no significant differences in diagnostic yield (p=0.604) (p=0.084). There were no complications or mortality. Conclusion: Scalene node biopsies are simply done under local anesthesia, without major complications. They have a high diagnostic yield regardless of the stages of the disease and lymph node size. We conclude that scalene node biopsy is a good alternative to other biopsy methods in sarcoidosis.
Keywords
Lymph nodes; Sarcoidosis;
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