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Clinial Analysis of Surgical Management for Descending Necrotizing Mediastinitis  

Yu, Jeong-Hwan (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Lim, Seung-Pyung (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University)
Lee, Seok-Ki (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Kim, Yong-Ho (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Kim, Si-Wook (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Kang, Shin-Kwang (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Yu, Jae-Hyeon (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Lee, Young (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
Publication Information
Journal of Chest Surgery / v.41, no.4, 2008 , pp. 463-468 More about this Journal
Abstract
Background: Descending necrotizing mediastinitis (DNM) is a life-threatening cervico-mediastinal infection extending from the oropharynx or periodontal space. We reviewed clinical outcomes of DNM patients that underwent surgical management. Material and Method: We analyzed the demographic and surgical data from 8 patients (6 males and 2 females) that underwent surgical management for DNM between August 2003 and August 2007. Result: The mean age was $56.6{\pm}12.3$ ($34{\sim}72$) years, Types of DNM were I (n=2), IIA (n=1), and IIB (n=5), based on the classification system of Endo et al. Four patients were septic at the time of operation. The infectious organism was identified in three cases and turned out to be Streptococcus. ICU stay was $24.3{\pm}17.9$ ($3{\sim}58$) days, and hospital stay was $49.1{\pm}33.8$ ($20{\sim}125$) days, There were two deaths (25%), both of which were due to multi-organ failure. Conclusion: Despite aggressive surgical drainage and appropriate medical management, DNM still had a high mortality rate, Early diagnosis and prompt surgical intervention are key to DNM management. In addition, transcervical drainage should be used in limited disease only.
Keywords
Mediastinitis; Necrosis; Analysis;
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