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Changes of Mitral Regurgitation after Aortic Valve Replacement, according to the Aortic Valve Pathology  

Kim, Si-Wook (Department of Thoracic and Cardiovascular Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine)
Lee, Young-Tak (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Jun, Tae-Gook (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Sung, Ki-Ick (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Kim, Wook-Sung (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Yang, Ji-Hyuk (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Choi, Jin-Ho (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Park, Pyo-Won (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Publication Information
Journal of Chest Surgery / v.40, no.10, 2007 , pp. 667-673 More about this Journal
Abstract
Background: Patients with severe aortic valve disease frequently display mitral valve regurgitation (MR). In such patients, the clinical course of MR after isolated aortic valve replacement (AVR) may be important for determining the treatment strategies. After isolated AVR, the change of the concomitant moderate degree or less of MR according to the type of aortic valve disease is not known well. The aim of this study was to analyze the post-operative changes of MR after performing AVR in those patients with severe AS (Group S) and those with severe AR (Group R). Material and Method: We retrospectively evaluated 43 patients with severe aortic disease and a moderate degree or less of mitral valve regurgitation, and these patients underwent isolated aortic valve replacement from January 1996 to June 2005. The patients were divided into two groups: the aortic valve stenosis group (n = 29) and the aortic valve regurgitation group (n = 14). The patients underwent transthoracic echocardiography preoperatively and at 7 days, $6{\sim}10$ months and more than 18 months (mean follow-up duration: 38 months) postoperatively. Result: The mean age was 60.9 years (Group S: 62 years, Group R: 52.5 years) and 60% (Group S=55%, Group R=71%) of the patients were male. The preoperative MR was mild in 29 (67.5%), mild to moderate in 11 (25.5%), and moderate in 3 (6.9%) patients. In the Group S patients, MR improved in 16 (55%) patients at the immediate postoperative days and in 17 (59%) patients at more than 18 months postoperatively. On the other hand, all the Group R patients exhibited earlier improvement. The decrease of LA size had a similar pattern to the MR change, but there were no significant differences in the change of the ejection fraction of the two groups. Conclusion: In the patients with severe aortic valve disease and concomitant low grade MR, the MR after AVR improved earlier and more effectively in the patients with AR than in those patients with AS.
Keywords
Heart valve disease; Aortic valve replacement; Mitral valve regurgitation;
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1 Jazayeri S, Gomez MC, Tatou E, et al. Clinical experience and doppler echocardiographic assessment of the first one hundred ATS AP (advanced performance) prosthetic valve in the aortic position. J Heart Valve Dis 2003;12:628-4   PUBMED
2 Christakis GT, Joyner CD, Morgan CD, et al. Left ventricular regression early after aortic valve replacement. Ann Thorac Surg 1996;62:1084-9   DOI   ScienceOn
3 Taniguchi K, Nakano S, Matsuda H, et al. Depressed myocardial contractility and normal ejection performance after aortic valve replacement in patients with aortic regurgitation. J Thorac Cardiovasc Surg 1989;98:258-65   PUBMED
4 Sutton M, Plappert T, Spigel A, et al. Early postoperative changes in left ventricular chamber size, architecture, and function in aortic stenosis and aortic regurgitation and their relation to intraoperative changes in afterload. Circulation 1987;76:77-89   DOI   PUBMED
5 Stahle E, Kvidal P, Nystrom SO, Bergstrom R. Long term relative survival after primary heart valve replacement. Eur J Cardiothorac Surg 1997;11:81-91   DOI   ScienceOn
6 Absil B, Dagenais F, Mathieu P, et al. Does moderate mitral regurgitation impact early or mid-term clinical outcome in patients undergoing isolated aortic valve replacement for aortic stenosis? Eur J Cardiothorac Surg 2003;24:217-22   DOI   ScienceOn
7 Moazami N, Diodato MD, Moon MR, et al. Does functional mitral regurgitation improve with isolated aortic valve replacement? J Card Surg 2004;19:444-8   DOI   ScienceOn
8 Barreiro CJ, Patel ND, Fitton TP, et al. Aortic valve replacement and concomitant mitral valve regurgitation in the elderly: impact on survival and functional outcome. Circulation 2005;112:I443-7   DOI
9 Muller XM, Tevaearai HT, Stumpe F, et al. Long term results of mitral-aortic valve operations. J Thoac Cardiovasc Surg 1998;115:1298-309   DOI   ScienceOn
10 Moon MR, Pasque MK, Munfakh NA, et al. Prosthesis- patient mismatch after aortic valve replacement: impact of age and body size on late survival. Ann Thorac Surg 2006;81:481-9   DOI   ScienceOn
11 Brasch AV, Khan SS, DeRobertis MA, Kong JHK, Chiu J, Siegel RJ. Change in mitral regurgitation severity after aortic valve replacement for aortic stenosis. Am J Cardiol 2000;85:1271-4   DOI   ScienceOn
12 Harris KM, Malenka DJ, Haney MF, et al. Improvement in mitral regurgitation after aortic valve replacement. Am J Cardiol 1997;80:741-5   DOI   ScienceOn
13 Maren EJ, Martin GK, Craig HS, Susan EW, Michael AA. Presence of mitral annular calcification predicts improvement in mitral regurgitation after aortic valve replacement for severe aortic stenosis. Am J Cardiol 1997;80:741-5   DOI   ScienceOn
14 Ruel M, Kapila V, Price J, Kulik A, Burwash IG, Mesana TG. Natural history and predictors of outcome in patients with concomitant functional mitral regurgitation at the time of aortic valve replacement. Circulation 2006;114:I541-6   DOI   ScienceOn
15 Goland S, Loutaty G, Arditi A, Snir E, Abend I, Caspi A. Improvement in mitral regurgitation after aortic valve replacement. Isr Med Assoc J 2003;5:12-4   PUBMED
16 Badano L, Mocchegiani R, Bertoli D, et al. Normal echocardiographic characteristics of the Sorin bicarbon bileaflet prosthetic heart valve in the mitral and aortic positions. J Am Soc Echocardiogr 1997;10:632-43   DOI   ScienceOn
17 Galloway AC, Grossi EA, Bauman FG, et al. Multiple valve operation for advanced valvular heart disease: result and risk factors in 518pts. J Am Coll Cardiol 1992; 19:1677-8   PUBMED
18 Rao L, Mohr-Kahaly S, Geil S, Dahm M, Meyer J. Left ventricular remodeling after aortic valve replacement. Z Kardiol 1999;88:283-9   DOI   ScienceOn