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Analysis of Neurological Complications on Antegrade Versus Retrograde Cerebral Perfusion in the Surgical Treatment of Aortic Dissection  

Park Il (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Kim Kyu Tae (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Lee Jong Tae (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Chang Bong Hyun (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Lee Eung Bae (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Cho Joon Yong (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kyungpook National University)
Publication Information
Journal of Chest Surgery / v.38, no.7, 2005 , pp. 489-495 More about this Journal
Abstract
In the surgical treatment of aortic dissection, aortic arch replacement under total circulatory arrest is often performed after careful inspection to determine the severity of disease progression. Under circulatory arrest, antegrade or retrograde cerebral perfusion is required for brain protection. Recently, antegrade cerebral perfusion has been used more, because of the limitation of retrograde cerebral perfusion. This study is to compare these two methods especially in the respect to neurological complications. Material and Method: Forty patients with aortic dissection involving aortic arch from May 2000 to May 2004 were enrolled in this study, and the methods of operation, clinical recovery, and neurological complications were retrospectively reviewed. Result: In the ACP (antegrade cerebral perfusion) group, axillary artery cannulation was performed in 10 out of 15 cases. In the RCP (retrograde cerebral perfusion) group, femoral artery Cannulation was performed in 24 out of 25 cases. The average esophageal and rectal temperature under total circulatory arrest was $17.2^{\circ}C\;and\;22.8^{\circ}C$ in the group A, and $16.0^{\circ}C\;and\;19.7^{\circ}C$ in the group B, respectively. Higher temperature in the ACP group may have brought the shorter operation and cardiopulmonary bypass time. However, the length of period for postoperative clinical recovery and admission duration did not show any statistically significant differences. Eleven out of the total 15 cases in the ACP group and thirteen out of the total 25 cases in the RCP group showed neurological complication but did not show statistically significant difference. In each group, there were 5 cases with permanent neurological complications. All 5 cases in the ACP group showed some improvements that enabled routine exercise. However all 5 cases in RCP group did not show significant improvements. Conclusion: The Antegrade, cerebral perfusion, which maintains orthordromic circulation, brings moderate degree of hypothermia and, therefore, shortens the operation time and cardiopulmonary bypass time. We concluded that Antegrade cerebral perfusion is safe and can be used widely under total circulatory arrest.
Keywords
Aortic dissection; Total circulatory arrest , induced; Cerebral perfusion; Neurological injury;
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