Browse > Article

Protamine Induced Anaphylactic Reaction after Cardiopulmonary Bypass -A case report-  

백종현 (영남대학교 의과대학 흉부외과학교실)
한승세 (영남대학교 의과대학 흉부외과학교)
이정철 (영남대학교 의과대학 흉부외과학교)
정태은 (영남대학교 의과대학 흉부외과학교)
이장훈 (영남대학교 의과대학 흉부외과학교)
이동협 (영남대학교 의과대학 흉부외과학교실)
Publication Information
Journal of Chest Surgery / v.37, no.7, 2004 , pp. 606-608 More about this Journal
Abstract
Anaphylactic reaction to protamine sulfate, which is used widely to reverse the anticoagulative effect of heparin after cardiopulmonary bypass, is very rare. But the result of anaphylactic reaction can be very fatal and the mechanism of it is still not clear. We report. a. case of severe anaphylactic reaction to protamine sulfate following the replacement of the mitral valve and .Maze procedure using microwave in a non-diabetic 57-year-old female patient.
Keywords
Anaphylaxis; Protamine; Drugs;
Citations & Related Records
연도 인용수 순위
  • Reference
1 High-titer protamine-specific IgG antibody associated with anaphylaxis: report of a case and quantitative analysis of antibody in vasectomized men /
[ Adourian,U.;Shampaine,E.L.;Hirshman,C.A.;Fuchs,E.;Adkinson,N.F.Jr. ] / Anesthesiology   DOI   ScienceOn
2 Suspected protamine allergy: diagnosis and management for coronary artery surgery /
[ Pharo,G.H.;Horrow,J.;Van Riper,D.F.;Levy,J.H. ] / Anesth Analg
3 Prospective evaluation of risk of protamine reactions in patients with NPH insulindependent diabetes /
[ Levy,J.H.;Zaidan,J.R.;Faraj,B. ] / Anesth Analg
4 Protamine-induced fatal anaphylaxis /
[ Sharath,M.D.;Metzger,W.J.;Richerson,H.B.(et al.) ] / J Thorac Cardiovasc Surg
5 Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine /
[ Weiss,M.E.;Nyhan,D.;Peng,Z.(et al.) ] / N Engl J Med   DOI   ScienceOn
6 Catastrophic cardiovascular adverse reactions to protamine are nitric oxide/cyclic guanosine monophosphate dependent and endothelium mediated /
[ Viaro,F.;Dalio,M.B.;Evora,P.R.B. ] / Chest   DOI   ScienceOn
7 Evaluation of patients at risk for protamine reactions /
[ Levy,J.H.;Schwieger,I.M.;Zaidan,J.R.;Faraj,B.A.;Weintraub,W.S. ] / J Thorac Cardiovasc Surg
8 Dramatic postcardiotomy outcome, due to severe anaphylactic reaction to protamine /
[ Panos,A.;Orrit,X.;Chevalley,C.;Kalangos,A. ] / Eur J Cardiothorac Surg   DOI   ScienceOn