Browse > Article

The Utility of Chest CT in Staging of Esophageal Cancer  

홍성범 (전남대학교 의과대학 흉부외과학교실)
장원채 (전남대학교 의과대학 흉부외과학교실)
김윤현 (전남대학교 의과대학 진단방사선과학교실)
김병표 (전남대학교 의과대학 흉부외과학교실)
최용선 (전남대학교 의과대학 흉부외과학교실)
오봉석 (전남대학교 의과대학 흉부외과학교실)
Publication Information
Journal of Chest Surgery / v.37, no.12, 2004 , pp. 992-998 More about this Journal
Abstract
Background: The decision of staging of esophageal cancer have great effect on the resectability of the lesion and estimation of the patient's prognosis. Today, CT is one of the most popular modality for staging of esophageal cancer. However, it has some limitations because of false-positive or false-negative findings on cancer staging. The purpose of this study was to analyze the efficacy of CT in preoperative staging of esophageal cancer. Material and Method: We retrospectively analysed the difference of staging of esophageal cancer between CT and histopathological findings for the 114 patients with histologically proven esophageal cancer who underwent operation at the department of thoracic and cardiovascular surgery, Chonnam national university hospital, between January 1999 and June 2003. We evaluated the efficacy of chest CT in the staging of esophageal cancer compared to postoperative histopathologic findings by calculating sensitivity, specificity, accuracy, and reproducibility of chest CT to detect abnormality. Result: The reproducibilities between chest CT and histopathologic findings were 0.32 (p<0.01) for primary tumor (T), 0.36 (p<0.01) for lymph node invasion (N), and 0.62 (p<0.01) for distant metastasis (M). The reproducibilities between chest CT and histopathologic findings for lymph node invasion (N) and distant metastasis (M) were superior to that of primary tumor (T). The accuracy of primary tumor (T) was 65.8% and 98.2% in group III and IV, which was significantly higher than that of group I and II (78.9% and 62.3%). In general, specificity of chest CT for TNM staging was superior to sensitivity. Conclusion: In conclusion, preoperative CT scanning can provide important information on lymph node invasion and metastasis of lesion than primary tumor invasion.
Keywords
Esophageal neoplasm; Computed tomography; Neoplasm staging;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Han KM, Lee JT, Yoo HS. Computed tomography in the staging of esophageal carcinoma. J Korean Radiol Soc 1986; 22:801-8.   DOI
2 Shim YM, Park SJ, Kim BT, Kim SC. Staging of esophageal cancer usingpositron emission tomography: comparing to computed tomography. Korean J Thorac Cardiovasc Surg 1999;32:388-93.
3 Japanese Committee for Registration of Esophageal Carcinoma. A proposal for a new TNM classification of esophageal carcinoma. Jpn J Clin Oncol 1985;14:625
4 Picus D, Dennis MB, Owen JW, et al. Computed tomography in the staging of esophageal cancer. Radiology 1983; 146:433-8.   DOI   PUBMED
5 Coulomb M, Lebas JF, Sarrazln R. Computed tomography and esophageal carcinoma. Radiology 1981;62:475-8.
6 Halber MD, Daffner RH, Thompson WM. CT of the esophagus. AJR 1979;133:1047-50.   DOI   ScienceOn
7 Freeny PC, Marks WM. Adenocarcinoma of the gastroesophageal junction; barium and CT examination. AJR 1982;138:1077-84   DOI   ScienceOn
8 Reinig JW, Stanley JH, Schbel SI. CT Evaluation of thickened esophageal wall. AJR 1983;140:931-4   DOI   ScienceOn
9 Akiyama H, Tsurumaru M, Kawamura T, Ono Y. Principles of surgical treatment for carcinoma of the esophagus: analysis of lymph node involvement. Ann Surg 1981;194: 438-46.   DOI   PUBMED   ScienceOn
10 Wallace MB, Nietert PJ, Earle C, et al. An analysis of multiple staging management strategies for carcinoma of the esophagus: computed tomography, endoscophy, endoscopic ultrasound, positron emission tomography, and thoracoscopy/ laparoscopy. Ann Thorac Surg 2002;74:1026-32.   DOI   ScienceOn
11 Oh BS, Min YI, Kim BY, Lee DJ. Short-term results of surgical treatment in esophageal carcinoma. Korean J Thorac Cardiovasc Surg 1992;25:398-404.
12 Rosenberg JC, Franklin R, Steiger Z. Squamous cell carcinoma of the thoracic esophagus: an interdisciplinary approach. Curr Probl Cancer 1981;5:1-52.   PUBMED
13 Kienle P, Buhl K, Kuntz C, et al. Prospective comparison of endoscopy, endosonography and computed tomography for staging of tumors of the esophagus and gastric cardia. Digestion 2002;66:230-6.   DOI   ScienceOn
14 Japanese Society for Esophageal Disease. Guidelines for the clinical and pathological studies on carcinoma of the esophagus. Jpn J Surg 1976;6:70.