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Primary Malignant Melanoma Presenting as an Anterior Mediastinal Mass  

김형렬 (서울대학교병원 흉부외과, 서울대학교 의과대학 흉부외과학교실)
이정상 (서울시립보라매병원 흉부외과, 서울대학교 의과대학 흉부외과교실)
김영태 (서울대학교병원 흉부외과, 서울대학교 의과대학 흉부외과학교실)
김주현 (서울대학교병원 흉부외과, 서울대학교 의과대학 흉부외과학교실)
김지은 (서울시립보라매병원 병리과, 서울대학교 의과대학 병리학교실)
Publication Information
Journal of Chest Surgery / v.35, no.9, 2002 , pp. 697-700 More about this Journal
Abstract
Primary malignant melanoma of the mediastinum is extremely rare : To date, there have been only 8 cases reported in the literature. We report a case of a 50-year-old woman presented with an anterior mediastinal mass. The mass invaded the lung parenchyme of right upper lobe, which was wedge-resected with the mass. Microscopically, spindle or polygonal tumor cells with prominent nucleoli and intracytoplasmic melanin pigments are characterized and Fontana stain confirmed the presence of melanin pigment. Immunohistochemical studies showed diffuse positive staining for HMB45, S100 protein and vimentin, which further suggested melanoma.
Keywords
Mediastinal neoplasms; Melanoma;
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