Antidiabetic Effects of Mixed Extract from Dendropanax morbiferus, Broussonetia kazinoki, and Cudrania tricuspidata
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Kim, Sol
(Jeonju AgroBio-Materials Institute)
Kim, Sang-Jun (Jeonju AgroBio-Materials Institute) Oh, Junseok (Dongbu Eastern Herbal Medicine Agricultural Association Corporation) Hong, Jae-Heoi (Dongbu Eastern Herbal Medicine Agricultural Association Corporation) Kim, Seon-Young (Jeonju AgroBio-Materials Institute) |
1 | Gomez-Valades AG, Mendez-Lucas A, Vidal-Alabro A, Blasco FX, Chillon M, Bartrons R, Bermudez J, Perales JC, Pck1 gene silencing in the liver improves glycemia control, insulin sensitivity, and dyslipidemia in db/db mice. Diabetes. 2008: 57: 2199-210. DOI |
2 | Evans JMM, Newton RW, Ruta DA, MacDonald TM, Morris AD, Socio-economic status, obesity and prevalence of Type 1 and Type 2 diabetes mellitus. Diabetic Med. 2000: 17: 478-80. DOI |
3 | Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ. Epidemiology of Type 1 Diabetes. Endocrin Metab Clin. 2010: 39: 481-97. DOI |
4 | Imamura F, Connor L,; Ye Z, Mursu J, Hayashino Y, Bhupathiraju SN, Forouhi NG. Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction. Brit J Sport Med 2016: 50: 496. DOI |
5 |
Kamata K, Mizukami H, Inaba W, Tsuboi K, Tateishi Y, Yoshida T, Yagihashi S. Islet amyloid with macrophage migration correlates with augmented |
6 | Rodriguez-Calvo T, Ekwall O, Amirian N, Zapardiel-Gonzalo J, von Herrath MG. Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes. Diabetes. 2014: 63: 3880-90. DOI |
7 |
Nopparat J,; Nualla-ong A, Phongdara A. Ethanolic extracts of Pluchea indica (L.) leaf pretreatment attenuates cytokine-induced |
8 | Wiernsperger NF, Bailey CJ. The antihyperglycaemic effect of metformin: therapeutic and cellular mechanisms. Drugs. 1999: 58: Suppl 1: 31-39: discussion 75-82. DOI |
9 | Amer Diabet A, Diagnosis and classification of diabetes mellitus American Diabetes Association. Diabetes care. 2011: 34: S62-S69. DOI |
10 | Klover PJ, Mooney RA. Hepatocytes: critical for glucose homeostasis. Int J Biochem Cell B. 2004: 36: 753-8. DOI |
11 | An NY, Kim J-E, Hwang D, Ryu HK. Anti-diabetic effects of aqueous and ethanol extract of Dendropanax morbifera Leveille in streptozotocin-induced diabetes model. J Nutr Health. 2014: 47: 394-402. DOI |
12 | Kim DH, Lee S, Chung YW, Kim BM, Kim H, Kim K, Yang KM. Antiobesity and Antidiabetes Effects of a Cudrania tricuspidata Hydrophilic Extract Presenting PTP1B Inhibitory Potential. BioMed Res Int. 2016: 2016: 8432759. DOI |
13 | Lee H, Li H, Jeong JH, Noh M, Ryu J-H. Kazinol B from Broussonetia kazinoki improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes. Fitoterapia. 2016: 112: 90-6. DOI |
14 |
Bae U-J, Jang H-Y, Lim JM, Hua L, Ryu J-H, Park B-H. Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced |
15 | Bae U-J, Lee DY, Song M-Y, Lee S-M, Park J-W, Ryu J-H, Park B-H. A Prenylated Flavan from Broussonetia kazinoki Prevents Cytokine-Induced &beta-Cell Death through Suppression of Nuclear Factor-kappa B Activity. Biol Pharm Bull. 2011: 34: 1026-31. DOI |
16 | Arnao MB. Some methodological problems in the determination of antioxidant activity using chromogen radicals: a practical case. Trends Food Sci Tech. 2000: 11: 419-421. DOI |
17 | van den Berg R, Haenen GRMM, van den Berg H, Bast A. Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chem. 1999: 66: 511-7. DOI |
18 | Liu ZQ, Liu T, Chen C, Li MY, Wang ZY, Chen RS, Wei GX, Wang XY, Luo DQ. Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice. Toxicol Appl Pharm. 2015, 285: 61-70. DOI |
19 | Hunyadi A, Martins A, Hsieh T-J, Seres A, Zupko I. Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats. Plos One. 2012: 7: e50619. DOI |
20 |
Habtemariam S. |
21 | Zhang Y, Liu D. Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulin secretory function. Eur J Pharmacol. 2011: 670: 325-32. DOI |
22 | Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002: 23: 599-622. DOI |
23 |
Tadera K, Minami Y, Takamatsu K, Matsuoka T. Inhibition of |
24 | Eizirik DL, Mandrup-Poulsen T. A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia. 2001: 44: 2115-33. DOI |
25 | Corbett JA, McDaniel ML. Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM. Diabetes. 1992: 41: 897-903. |
26 | Cordero-Herrera I, Martin MA, Goya L, Ramos S. Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells. Food Chem Toxicol. 2014: 64: 10-19. DOI |
27 | Xu J, Ma M, Purcell WM. Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers. Toxicol Appl Pharm. 2003: 189: 100-11. DOI |
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