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http://dx.doi.org/10.5407/jksv.2017.15.1.047

In-droplet preconcentration of microparticles using surface acoustic waves  

Park, Kwangseok (Dept. of Mechanical Engineering, KAIST)
Park, Jinsoo (Dept. of Mechanical Engineering, KAIST)
Jung, Jin Ho (Dept. of Mechanical Engineering, KAIST)
Destgeer, Ghulam (Dept. of Mechanical Engineering, KAIST)
Ahmed, Husnain (Dept. of Mechanical Engineering, KAIST)
Ahmad, Raheel (Dept. of Mechanical Engineering, KAIST)
Sung, Hyung Jin (Dept. of Mechanical Engineering, KAIST)
Publication Information
Journal of the Korean Society of Visualization / v.15, no.1, 2017 , pp. 47-52 More about this Journal
Abstract
In droplet-based microfluidic systems, in-droplet preconcentration of a sample is one of the important prerequisites for biochemical or medical analysis. There have been a few studies on preconcentration in a moving droplet, but they are limited to practical applications since 1) their method are time-consuming or 2) they require specific properties such as electric and magnetic properties. In this study, we demonstrated the position control of polystyrene particles of 5 and $10{\mu}m$ in diameter inside a moving water-in-oil droplet using traveling surface acoustic waves. Since the frequencies for effective control of each diameter were found, microparticles with no labels could be utilized. In addition, the proposed method enabled on-demand preconcentration inside a polydimethylsiloxane microchannel. In-droplet preconcentration of microparticles was realized by splitting a mother droplet with manipulated particles at a downstream bifurcation zone. Given these advantages, the proposed system is a promising acoustofluidic lab-on-a-chip platform for preconcentration inside a droplet.
Keywords
In-droplet particle preconcentration; Surface acoustic waves; Acoustomicrofluidics; Droplet microfluidic system;
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