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Expression Patterns of P21-Activated Kinase 2 by Sterne Spores on Human Macrophages  

Seo Gwi-Moon (Hanyang University)
Jung Kwang-Hwa (Hanyang University)
Kwak Hyun Jung (Hanyang University)
Kim Seong-Joo (Hanyang University)
Kim Ji-Chon (Hanyang University)
Chai Young-Gyu (Hanyang University)
Publication Information
Journal of the Korea Institute of Military Science and Technology / v.7, no.4, 2004 , pp. 87-90 More about this Journal
Abstract
In order to elucidate the mechanism of infection on human macrophages, we peformed the 2-dimensional electrophoresis and the western blot analysis using the infected human macrophages with the spores of live and inactivated Sterne. We confirmed P21-activated kinase 2 protein which related to cell death(apoptosis) human macrophages at the early stage events. The inhibition of the P21-activated protein kinase 2 protein will be reduced apoptosis on infected human macrophages with Sterne spores.
Keywords
p21 자동인산화효소;아포;이차원전기영동;세포사멸;단백질체학;
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