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http://dx.doi.org/10.3347/kjp.2015.53.6.713

A Case of Ocular Angiostrongyliasis with Molecular Identification of the Species in Vietnam  

Nguyen, Van De (Department of Parasitology, Hanoi Medical University)
Le, Van Duyet (Department of Immunology, Institute of Bio-Technology)
Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine)
Publication Information
Parasites, Hosts and Diseases / v.53, no.6, 2015 , pp. 713-717 More about this Journal
Abstract
A 23-year-old female residing in a village of Cao Bang Province, North Vietnam, visited the Hospital of Hanoi Medical University in July 2013. She felt dim eyes and a bulge-sticking pain in her left eye for some days before visiting the hospital. In the hospital, a clinical examination, an eye endoscopy, and an operation were carried out. A nematode specimen was collected from the eye of this patient. The body of this worm was thin and long and measured $22.0{\times}0.3mm$. It was morphologically suggested as an immature female worm of Angiostrongylus cantonensis. By a molecular method using 18S rRNA gene, this nematode was confirmed as A. cantonensis. This is the first molecular study for identification of A. cantonensis in Vietnam.
Keywords
Angiostrongylus cantonensis; eosinophilic meningoencephalitis; eye;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Spratt DM. Species of Angiostrongylus (Nematoda: Metastrongyloidea) in wildlife: a review. Int J Parasitol Parasites Wildl 2015; 4: 178-189.   DOI
2 Miyazaki I. Angiostrongyliasis. In Helminthic Zoonoses. Tokyo, Japan. International Medical Foundation of Japan. 1991, pp 347-355.
3 Rosen L, Chappell R, Laqueur GL, Wallace GD, Weinstein PP. Eosinophilic meningoencephalitis caused by a metastrongylid lung-worm of rats. JAMA 1962; 179: 620-624.   DOI
4 Phan TN. Angiostrongylus cantonensis. In Textbook for Training Medical Doctors of Hanoi University. Hanoi, Vietnam. National Hospital of Tropical Diseases. 2009, pp. 246-247 (in Vietnamese).
5 An PN. Some comments for eosinophilic meningoencephalitis in children in National Hospital of Children from 1995 to 2000. J Pract Med 2002; No. 3: 66-69 (in Vietnamese).
6 De NV. Report of eosinophilic meningoencephalitis caused by Angiostrongylus. J Pharm-Med Inform 2004; No. 5: 15-16 (in Vietnamese).
7 Hwang KP, Chen ER. Clinical studies on Angiostrongylus cantonensis among children in Taiwan. Southeast Asian J Trop Med Public Health 1991; 22(suppl): 194-199.
8 De NV, An PN, Huong TTT. Eosinophilic meningoencephalitis caused by Angiostrongylus. J Pharm-Med Inform 2008; No. 11: 9-13.
9 Xuan LT, Dung DH, Hien TV. A case infected by Angiostrongylus cantonensis in the eye in Ho Chi Minh City. J Med Ho Chi Minh City 2001; No. 1: 97-100 (in Vietnamese).
10 Feng Y, Nawa Y, Sawanyavisuth K, Lv Z, Wu ZD. Comprehensive review of ocular angiostrongyliasis with special reference to optic neuritis. Korean J Parasitol 2013; 51: 613-619.   DOI
11 Tamura K, Nei M, Kumar S. Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci USA 2004; 101: 11030-11035.   DOI
12 Qvarnstrom Y, da Silva ACA, Teem JL, Hollingsworth R, Bishop H, Graeff-Teixeira C, da Silva AJ. Improved molecular detection of Angiostrongylus cantonensis in mollusks and other environmental samples with a species-specific internal transcribed spacer 1-based TaqMan assay. Appl Environ Microbiol 2010; 76: 5287-5289.   DOI
13 Liu YJ, Han YP, Li ZY, Wei J, He HJ, Xu CZ, Zheng HQ, Zhan XM, Wu ZD, Lv ZY. Molecular cloning and characterization of cystatin, a cysteine protease inhibitor, from Angiostrongylus cantonensis. Parasitol Res 2010; 107: 915-922.   DOI
14 Jefferies R, Shaw SE, Willesen J, Viney ME, Morgan ER. Elucidating the spread of the emerging canid nematode Angiostrongylus vasorum between Palearctic and Nearctic ecozones. Infect Genet Evol 2010; 10: 561-568.   DOI