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http://dx.doi.org/10.3347/kjp.2013.51.5.519

Breast-Feeding Protects Infantile Diarrhea Caused by Intestinal Protozoan Infections  

Abdel-Hafeez, Ekhlas Hamed (Department of Parasitology, Faculty of Medicine, Minia University)
Belal, Usama Salah (Department of Parasitology, Faculty of Medicine, Minia University)
Abdellatif, Manal Zaki Mohamed (Department of Parasitology, Faculty of Medicine, Minia University)
Naoi, Koji (Medical Corporation Kohitsujikai)
Norose, Kazumi (Department of Infection and Host Defense, Graduate School of Medicine)
Publication Information
Parasites, Hosts and Diseases / v.51, no.5, 2013 , pp. 519-524 More about this Journal
Abstract
This study investigated the effect of breast-feeding in protection against protozoan infection in infants with persistent diarrhea. Infants were classified into 2 groups; 161 breast-fed infants and the same number of non-breast-fed infants. Microscopic examinations of stool were done for detection of parasites and measuring the intensity of infection. Moreover, serum levels of IgE and TNF-${\alpha}$ were measured by ELISA. Cryptosporidium spp., Entamoeba histolytica/Entamoeba dispar, Giardia lamblia, and Blastocystis sp. were demonstrated in infants with persistent diarrhea. The percentage of protozoan infections was significantly lower in breast-fed infants than that in the non-breast-fed infants. The levels of IgE and TNF-${\alpha}$ were significantly lower in the breast-fed group than in the non-breast-fed group. There were significant positive associations between the serum levels of IgE and TNF-${\alpha}$ and the intensity of parasite infection in the breast-fed group. It is suggested that breast-feeding has an attenuating effect on the rate and intensity of parasite infection.
Keywords
Entamoeba histolytica; Entamoeba dispar; Giardia lamblia; Cryptosporidium; Blastocystis; breast-feeding; breast milk; diarrhea; intestinal protozoa; IgE; TNF-${\alpha}$;
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