Browse > Article
http://dx.doi.org/10.3347/kjp.2012.50.4.339

An Outbreak of Trichinosis with Molecular Identification of Trichinella sp. in Vietnam  

Nguyen, Van De (Department of Parasitology, Hanoi Medical University)
Nguyen, Vu Trung (National Hospital of Tropical Diseases)
Nguyen, Hong Ha (National Hospital of Tropical Diseases)
Vu, Thi Nga (National Centre for Veterinary Diagnosis)
Nguyen, Minh Ha (National Hospital of Tropical Diseases)
Pham, Thanh Thuy (Bach Mai Hospital)
Le, Van Duyet (National Hospital of Tropical Diseases)
Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine)
Publication Information
Parasites, Hosts and Diseases / v.50, no.4, 2012 , pp. 339-343 More about this Journal
Abstract
The 5th outbreak of trichinosis occurred in a mountainous area of North Vietnam in 2012, involving 24 patients among 27 people who consumed raw pork together. Six of these patients visited several hospitals in Hanoi for treatment. Similar clinical symptoms appeared in these patients within 5-8 days after eating infected raw pork, which consisted of fever, muscle pain, difficult moving, edema, difficult swallowing, and difficult breathing. ELISA revealed all (6/6) positive reactions against Trichinella spiralis antigen and all cases showed positive biopsy results for Trichinella sp. larvae in the muscle. The larvae detected in the patients were identified as T. spiralis (Vietnamese strain) by the molecular analysis of the mitochondrial cytochrome c oxidase subunit III (cox3) gene.
Keywords
Trichinella spiralis; muscle pain; pork; fever; ELISA; Vietnam;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Cook GC. Trichinosis (Trichinella spiralis). Manson's Tropical Diseases. London, UK. W.B. Saunder Co. Ltd. 1997. p. 1403-1407.
2 De NV, Dorny P, Waikagul J. Trichinelliasis in Vietnam. Seminar on Food- and Water-borne Parasitic Zoonoses (5th FBPZ), 28-30 November 2006.
3 Intapan PM, Chotmongkol V, Tantrawatpan C, Sanpool O, Morakote N, Maleewong W. Molecular identification of Trichinella papuae from a Thai patient with imported trichinellosis. Am J Trop Med Hyg 2011; 84: 994-997.   DOI   ScienceOn
4 Miyazaki I. Trichinelliasis. Helminthic Zoonoses. Tokyo, Japan. Southeast Asian Medical Information Center. 1991. p. 452-459.
5 Owen IL, Morales G, Pezzotti MA, Pozio E. Trichinella infection in a hunting population of Papua New Guinea suggests an ancient relationship of Trichinella with human beings. Trans R Trop Med Hyg 2005; 99: 618-624.   DOI   ScienceOn
6 Pozio E. World distribution of Trichinella spp. infections in animals and humans. Vet Parasitol 2007; 149: 3-21.   DOI   ScienceOn
7 Sohn WM, Huh S, Chung DI, Pozio E. Molecular identification of Korean Trichinella isolates. Korean J Parasitol 2003; 41: 125-126.   과학기술학회마을   DOI   ScienceOn
8 Vu Thi N, Dorny P, La Rosa G, To Long T, Nguyen Van C, Pozio E. High prevalence of anti-Trichinella IgG in domestic pigs of the Son La province, Vietnam. Vet Parasitol 2010; 168: 136-140.   DOI   ScienceOn
9 Tamura K, Nei M, Kumar S. Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci USA 2007; 101: 11030-11035.