Browse > Article

Seroprevalence of Toxocara antibodies among patients suspected of ocular toxocariasis in Slovenia  

Logar, Jernej (Department of Parasitology, Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana)
Soba, Barbara (Department of Parasitology, Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana)
Kraut, Aleksandra (Department of Ophthalmology, University Medical Center Ljubljana)
Branka, Stirn-Kranjc (Department of Ophthalmology, University Medical Center Ljubljana)
Publication Information
Parasites, Hosts and Diseases / v.42, no.3, 2004 , pp. 137-140 More about this Journal
Abstract
Ocular toxocariasis named also ocular larva migrans is caused by larvae of the roundworm Toxocara spp. The purpose of this study was to find out the seroprevalence of Toxocara antibodies in patients suspected of ocular toxocariasis. Between January 2001 and December 2003, sera from 239 ocular patients, aged 3 to 80 years, were examined by ELISA and confirmed by Western blot test. Out of the 239 patients, 172 (72%) were seronegative and 67 (28%) were Toxocara seropositive; 95% CI (22-34%). The median age of Toxocara seropositive patients was 37.6 years. There was no significant difference in the number of Toxocara positive sera between the younger age group (${\leq}14$ years) and the older age group (>14 years), p>0.05. A high rate of Toxocara seropositivity in ocular patients should alert the ophthalmologists in Slovenia to include toxocariasis in the differential diagnosis of eye diseases more frequently.
Keywords
Toxocara; toxocariasis; eye infections; serology; ELISA; Western blot; Slovenia;
Citations & Related Records

Times Cited By SCOPUS : 9
연도 인용수 순위
1 Magnaval JF, Glickman LT, Dorchies P, Morassin B (2001) Highlights of human toxocariasis. Korean J Parasitol 2001;39: 1-11   DOI   ScienceOn
2 Nichols RL, (1956) The etiology of visceral larva migrans: I. Diagnostic morphology of infective secend-stage Toxocara larvae. J Parasitol 42: 349-362   DOI   ScienceOn
3 Petithory JC, Chaumeil C, Liotet S, Rosseau M, Bisognani C (1993) Immunological studies on ocular larva migrans. In Toxocara and toxocariasis; clinical, epidemiological and molecular perspectives, Lewis JW, Maizels RM (eds.). p81-89, The British Society for Parasitology with the Institute of Biology, London, UK
4 Taylor MR (2001) The epidemiology of ocular toxocariasis. J Helminthol 75: 109-118   PUBMED
5 Wilder HC (1950) Nematode endophthalmitis. Trans Am Acad Ophthalmol Otolaryngol 51: 99-109
6 Wolfe A, Wright IP (2003) Human toxocariasis and direct contact with dogs. Vet Rec 152: 419-422   DOI   ScienceOn
7 Sakai R, Kawashima H, Shibui H, Kamata K, Kambara C, Matsouka H (1998) Toxocara cati-induced ocular toxocariasis. Arch Ophthalmol 116: 1686-1687   PUBMED
8 Sabrosa NA, de Souza EC (2001) Nematode infection of the eye: toxocariasis and diffuse unilateral subacute neu-roretinitis. Curr Opin Ophthalmol 12: 450-454   DOI   ScienceOn
9 Fisher M (2003) Toxocara cati: an underestimated zoonotic agent. Trends Parasitol 19: 167-170   DOI   ScienceOn
10 Samson CM, Ekong A, Foster CS (2001) Uveitis in children: diagnosis and management. Int Ophthalmol Clin 41: 199-216   DOI   ScienceOn
11 Logar J, Karut A, Likar M (1993) Toxocara antibodies in patients with visceral or ocular disorder in Slovenia. Infection 21: 27-29   DOI