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http://dx.doi.org/10.1016/j.jgr.2020.09.004

Adaptogenic effects of Panax ginseng on modulation of immune functions  

Ratan, Zubair Ahmed (School of Health and Society, University of Wollongong)
Youn, Soo Hyun (R&D Headquarters, Korea Ginseng Corporation)
Kwak, Yi-Seong (R&D Headquarters, Korea Ginseng Corporation)
Han, Chang-Kyun (R&D Headquarters, Korea Ginseng Corporation)
Haidere, Mohammad Faisal (Department of Soil, Water and Environment, University of Dhaka)
Kim, Jin Kyeong (Department of Integrative Biotechnology, Sungkyunkwan University)
Min, Hyeyoung (College of Pharmacy, Chung-Ang University)
Jung, You-Jung (Biological Resources Utilization Department, National Institute of Biological Resources)
Hosseinzadeh, Hassan (School of Health and Society, University of Wollongong)
Hyun, Sun Hee (R&D Headquarters, Korea Ginseng Corporation)
Cho, Jae Youl (Department of Integrative Biotechnology, Sungkyunkwan University)
Publication Information
Journal of Ginseng Research / v.45, no.1, 2021 , pp. 32-40 More about this Journal
Abstract
Traditional medicinal practices have used natural products such as adaptogens to treat inflammatory, autoimmune, neurodegenerative, bacterial, and viral diseases since the early days of civilization. Panax ginseng Myer is a common herb used in East Asian countries for millennia, especially in Korea, China, and Japan. Numerous studies indicate that ginseng can modulate the immune system and thereby prevent diseases. Although the human immune system comprises many different types of cells, multiple studies suggest that each type of immune cell can be controlled or stimulated by ginseng or its derivatives. Provisional lists of ginseng's potential for use against viruses, bacteria, and other microorganisms suggest it may prove to be a valuable pharmaceutical resource, particularly if higher-quality evidence can be found. Here, we reviewed the role of ginseng as an immune-modulating agent in attempt to provide a valuable starting point for future studies on the herb and the human immune system.
Keywords
Adaptogen; Immune function; Panax ginseng Myer; Innate immunity; Adaptive immunity;
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