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http://dx.doi.org/10.1016/j.jgr.2017.04.004

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL-/- mice  

Saba, Evelyn (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University)
Kim, Seung-Hyung (Institute of Traditional Medicine & Bioscience, Daejeon University)
Kim, Sung-Dae (Research Center, Dongnam Institute of Radiological and Medical Sciences)
Park, Sang-Joon (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University)
Kwak, Dongmi (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University)
Oh, Jun-Hwan (R&D Headquarters, Korean Ginseng Corporation)
Park, Chae-Kyu (R&D Headquarters, Korean Ginseng Corporation)
Rhee, Man Hee (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University)
Publication Information
Journal of Ginseng Research / v.42, no.3, 2018 , pp. 352-355 More about this Journal
Abstract
In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in $LDL^{-/-}$ mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.
Keywords
antiatheromatic; antidiabetic; antihypercholesterolemic; Rg3-enriched Korean Red Ginseng extract;
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