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http://dx.doi.org/10.1016/j.jgr.2016.03.003

Implications of red Panax ginseng in oxidative stress associated chronic diseases  

Lee, Yoon-Mi (Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University)
Yoon, Haelim (Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University)
Park, Hyun-Min (Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University)
Song, Byeng Chun (Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University)
Yeum, Kyung-Jin (Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University)
Publication Information
Journal of Ginseng Research / v.41, no.2, 2017 , pp. 113-119 More about this Journal
Abstract
The steaming process of Panax ginseng has been reported to increase its major known bioactive components, ginsenosides, and, therefore, its biological properties as compared to regular Panax ginseng. Biological functions of red Panax ginseng attenuating pro-oxidant environments associated with chronic diseases are of particular interest, since oxidative stress can be a key contributor to the pathogenesis of chronic diseases. Additionally, proper utilization of various biomarkers for evaluating antioxidant activities in natural products, such as ginseng, can also be important to providing validity to their activities. Thus, studies on the effects of red ginseng against various diseases as determined in cell lines, animal models, and humans were reviewed, along with applied biomarkers for verifying such effects. Limitations and future considerations of studying red ginseng were been discussed. Although further clinical studies are warranted, red ginseng appears to be beneficial for attenuating disease-associated symptoms via its antioxidant activities, as well as for preventing oxidative stress-associated chronic diseases.
Keywords
antioxidant; bioactives; Panax ginseng; red ginseng;
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Times Cited By KSCI : 11  (Citation Analysis)
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