Korean Red Ginseng Powder in the Treatment of Melasma: An Uncontrolled Observational Study |
Song, Margaret
(Department of Dermatology, Pusan National University School of Medicine)
Mun, Je-Ho (Department of Dermatology, Pusan National University School of Medicine) Ko, Hyun-Chang (Department of Dermatology, Pusan National University School of Medicine) Kim, Byung-Soo (Department of Dermatology, Pusan National University School of Medicine) Kim, Moon-Bum (Department of Dermatology, Pusan National University School of Medicine) |
1 | Kim EJ, Park HY, Yaar M, Gilchrest BA. Modulation of vascular endothelial growth factor receptors in melanocytes. Exp Dermatol 2005;14:625-633. DOI ScienceOn |
2 | Kim EH, Kim YC, Lee ES, Kang HY. The vascular characteristics of melasma. J Dermatol Sci 2007;46:111-116. DOI ScienceOn |
3 | Kupper TS, Min K, Sehgal P, Mizutani H, Birchall N, Ray A, May L. Production of IL-6 by keratinocytes. Implications for epidermal inflammation and immunity. Ann N Y Acad Sci 1989;557:454-464. |
4 | Kondo S, Kono T, Sauder DN, McKenzie RC. IL-8 gene expression and production in human keratinocytes and their modulation by UVB. J Invest Dermatol 1993;101:690-694. DOI ScienceOn |
5 | Eller MS, Ostrom K, Gilchrest BA. DNA damage enhances melanogenesis. Proc Natl Acad Sci U S A 1996;93:1087-1092. DOI ScienceOn |
6 | Lee EH, Cho SY, Kim SJ, Shin ES, Chang HK, Kim DH, Yeom MH, Woe KS, Lee J, Sim YC et al. Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2. J Invest Dermatol 2003;121:607-613. DOI ScienceOn |
7 | Lee HJ, Kim SR, Kim JS, Moon CJ, Kim JC, Bae CS, Jang JS, Jo SK, Kim SH. The effect of red ginseng on epidermal melanocytes in ultraviolet B-irradiated mice. J Ginseng Res 2006;30:188-193. 과학기술학회마을 DOI ScienceOn |
8 | Kim S, Kang BY, Cho SY, Sung DS, Chang HK, Yeom MH, Kim DH, Sim YC, Lee YS. Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin. Biochem Biophys Res Commun 2004;316: 348-355. DOI ScienceOn |
9 | Lee TK, Johnke RM, Allison RR, O'Brien KF, Dobbs LJ Jr. Radioprotective potential of ginseng. Mutagenesis 2005;20:237-243. DOI ScienceOn |
10 | Lee HJ, Kim SR, Kim JS, Moon CJ, Kim JC, Bae CS, Jang JS, Jo SK, Kim SH. The effect of red ginseng on ultraviolet-B induced skin damages in mouse. J Ginseng Res 2006;30:194-198. 과학기술학회마을 DOI ScienceOn |
11 | So SH, Lee SK, Hwang EI, Koo BS, Han GH, Chung JH, Lee MJ, Kim NM. Mechanism of Korean red ginseng and herb extracts (KTN0345) for anti-wrinkle activity. J Ginseng Res 2008;32:39-47. DOI ScienceOn |
12 | Balkrishnan R, McMichael AJ, Camacho FT, Saltzberg F, Housman TS, Grummer S, Feldman SR, Chren MM. Development and validation of a health-related quality of life instrument for women with melasma. Br J Dermatol 2003;149:572-577. DOI ScienceOn |
13 | Piamphongsant T. Treatment of melasma: a review with personal experience. Int J Dermatol 1998;37:897-903. DOI ScienceOn |
14 | Ni Z, Mu Y, Gulati O. Treatment of melasma with Pycnogenol. Phytother Res 2002;16:567-571. DOI ScienceOn |
15 | Yamakoshi J, Otsuka F, Sano A, Tokutake S, Saito M, Kikuchi M, Kubota Y. Lightening effect on ultraviolet-induced pigmentation of guinea pig skin by oral administration of a proanthocyanidin-rich extract from grape seeds. Pigment Cell Res 2003;16:629-638. DOI ScienceOn |
16 | Ortonne JP, Arellano I, Berneburg M, Cestari T, Chan H, Grimes P, Hexsel D, Im S, Lim J, Lui H et al. A global survey of the role of ultraviolet radiation and hormonal influences in the development of melasma. J Eur Acad Dermatol Venereol 2009;23:1254-1262. DOI ScienceOn |
17 | Yamakoshi J, Sano A, Tokutake S, Saito M, Kikuchi M, Kubota Y, Kawachi Y, Otsuka F. Oral intake of proanthocyanidin- rich extract from grape seeds improves chloasma. Phytother Res 2004;18:895-899. DOI ScienceOn |
18 | Kang WH, Yoon KH, Lee ES, Kim J, Lee KB, Yim H, Sohn S, Im S. Melasma: histopathological characteristics in 56 Korean patients. Br J Dermatol 2002;146:228-237. DOI ScienceOn |
19 | Horikoshi T, Nakahara M, Kaminaga H, Sasaki M, Uchiwa H, Miyachi Y. Involvement of nitric oxide in UVB-induced pigmentation in guinea pig skin. Pigment Cell Res 2000;13:358-363. DOI ScienceOn |
20 | Peak JG, Woloschak GE, Peak MJ. Enhanced expression of protein kinase C gene caused by solar radiation. Photochem Photobiol 1991;53:395-397. DOI ScienceOn |
21 | Nam KY. Clinical applications and efficacy of Korean ginseng. J Ginseng Res 2002;26:111-131. 과학기술학회마을 DOI ScienceOn |
22 | Choi JH, Oh DH. Effect of white and red ginseng extract on the immunological activities in lymphocytes isolated from sasang constitution blood cells. J Ginseng Res 2009; 33:33-39. DOI ScienceOn |
23 | Kim EH, Rhee DK. Anti-oxidative properties of ginseng. J Ginseng Res 2009;33:1-7. 과학기술학회마을 DOI ScienceOn |
24 | Kahn V, Ben-Shalom N. Effect of maltol on the oxidation of DL-DOPA, dopamine, N-acetyldopamine (NADA), and norepinephrine by mushroom tyrosinase. Pigment Cell Res 1997;10:139-149. DOI ScienceOn |
25 | Kimbrough-Green CK, Griffiths CE, Finkel LJ, Hamilton TA, Bulengo-Ransby SM, Ellis CN, Voorhees JJ. Topical retinoic acid (tretinoin) for melasma in black patients. A vehicle-controlled clinical trial. Arch Dermatol 1994;130:727-733. DOI |
26 | Lim JY, Ishiguro K, Kubo I. Tyrosinase inhibitory p-coumaric acid from ginseng leaves. Phytother Res 1999; 13:371-375. DOI ScienceOn |
27 | Lee JH, Lee BS, Yang MS, Byun BS, Kim WG, Kim BH, Lee SJ. Prevention of photoaging and wrinkle formation in hairless mice dorsal skin by AP3-03. Korean J Food Sci Technol 2005;37:989-996. 과학기술학회마을 |
28 | Hwang EY, Kong YH, Lee YC, Kim YC, Yoo KM, Jo YO, Choi SY. Comparison of phenolic compounds contents between white and red ginseng and their inhibitory effect on melanin biosynthesis. J Ginseng Res 2006;30:82-87. 과학기술학회마을 DOI ScienceOn |
29 | Taylor S, Westerhof W, Im S, Lim J. Noninvasive techniques for the evaluation of skin color. J Am Acad Dermatol 2006;54(5 Suppl 2):S282-S290. DOI ScienceOn |
30 | Grimes PE. Melasma. Etiologic and therapeutic considerations. Arch Dermatol 1995;131:1453-1457. DOI |
31 | Gupta AK, Gover MD, Nouri K, Taylor S. The treatment of melasma: a review of clinical trials. J Am Acad Dermatol 2006;55:1048-1065. DOI ScienceOn |
32 | Jang SK, Kim JH, Chung YS, Ahn DC, Kang MJ, Lee DG, Kim SH. An experimental study on the effect of immunopotential and the anticancer effect of red ginseng extract. Korean J Ginseng Sci 1994;18:151-159. 과학기술학회마을 |
33 | Wang Y, Wang BX, Liu TH, Minami M, Nagata T, Ikejima T. Metabolism of ginsenoside Rg1 by intestinal bacteria. II. Immunological activity of ginsenoside Rg1 and Rh1. Acta Pharmacol Sin 2000;21:792-796. |
34 | Chen XC, Zhu YG, Wang XZ, Zhu LA, Huang C. Protective effect of ginsenoside Rg1 on dopamine-induced apoptosis in PC12 cells. Acta Pharmacol Sin 2001;22:673-678. |