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http://dx.doi.org/10.5142/JGR.2008.32.1.019

Effects of Lipid Soluble Ginseng Extract on Immune Response  

Kim, Dong-Chung (Institute of Basic Science, Sungkyunkwan University)
Hwang, Woo-Ik (Department of Biochemistry, College of Medicine, Korea University)
In, Man-Jin (Department of Human Nutrition and Food Science, Chungwoon University)
Lee, Sung-Dong (Department of Food and Nutrition, College of Health Science, Korea University)
Publication Information
Journal of Ginseng Research / v.32, no.1, 2008 , pp. 19-25 More about this Journal
Abstract
Lipid soluble ginseng extract was administered by oral route in doses of 600 mg/patient daily in cancer patients over 2 months and 6 months. The administration of ginseng extract in cancer patients maintained the ratio of CD4/CD8 and number of the natural killer cell in the normal range during the administration period. Also its administration showed a positive effect on tumor values in 87.5% of patients in 2 month-group and in 50% of patients in 6 month-group, as determined by various cancer markers. Liver and kidney functions maintained normal condition during administration period of 6 months. Although there was no statistical significance, these data suggest that lipid soluble ginseng extract may be useful as an adjuvant therapeutic agent and nutritional supplement for the improvement of immune function and health in cancer patients. This study would provide the basis for the research in which the antitumor and immunopotential activity of lipid soluble ginseng extract for cancer patients are evaluated in formal clinical trial with statistically significant patient number.
Keywords
lipid soluble ginseng extract; cancer patients; adjuvant therapeutic; immunopotential;
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