Inhibitory Effect of Protopanxatriol Ginsenosides in an Oxazolone-induced Mouse Psoriatic Model |
Shin, Young-Wook
(College of Pharmacy, Kyung Hee University)
Bae, Eun-Ah (Department of Food and Nutrition, Kyung Hee University) Han, Myung-Joo (Department of Food and Nutrition, Kyung Hee University) Kim, Dong-Hyun (College of Pharmacy, Kyung Hee University) |
1 | Park, E.K., Choo, M.K., Han, M.J. and Kim, D.H.: Ginsenoside Rh1 possesses antiallergic and anti-inflammatory activities. Int. Arch. Allergy Immunol. 133, 113-120 (2004) DOI ScienceOn |
2 | Mochizuki, M., Yoo, C.Y., Matsuzawa, K., Sato, K., Saiki, I., Tono-oka, S., Samukawa, K. and Azuma, I.: Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside Rb2, 20(R)- and 20(S)-ginsenoside Rg3, of Red ginseng. Biol. Pharm. Bull. 18, 1197-1202 (1995) DOI ScienceOn |
3 | Sakuma, S., Higashi, Y., Sato, N., Sasakawa, T., Sengoku, T., Ohkubo, Y., Amaya, T. and Goto, T.: Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids). Int. Immunopharmacol. 1, 1219-1226 (2001) DOI ScienceOn |
4 | Friedman, E.S., LaNatra, N. and Stiller, M.J.: NSAIDs in dermatologic therapy: review and preview. J. Cutan. Med. Surg. 6, 449-459 (2003) |
5 | Hernandez, G.L., Volpert, O.V., Iniguez, M.A., Lorenzo, E., Martinez-Martinez, S., Grau, R., Fresno, M. and Redondo, J.M.: Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J. Exp. Med. 193, 607-620 (2001) DOI |
6 | Fujii, Y., Takeuchi, H., Tanaka, K., Sakuma, S., Ohkubo, Y. and Mutoh, S.: Effects of FK-506 (tacrolimus hydrate) on chronic oxazolone-induced dermatitis in rats. Eur. J. Pharmacol. 456, 115-121 (2002) DOI ScienceOn |
7 | Shin, Y.W., Bae, E.A., Kim, S.S., Lee, Y.C. and Kim, D.H.: Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis. Int. Immunopharmacol. 5, 1183-1191 (2005) DOI ScienceOn |
8 | Wakabayashi, C., Hasegawa, H., Murata, J. and Saiki, I.: In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 9, 411-417 (1998) |
9 | Akao, T., Kida, H., Kanaoka, M., Hattori, M. and Kobashi, K.: Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng. J. Pharm Pharmacol. 50, 1155-1160 (1988) |
10 | Akao, T., Kanaoka, M. and Kobashi, K.: Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administrationmeasurement of compound K by enzyme immunoassay: Biol. Pharm. Bull. 21, 245-249 (1988) |
11 | Shibata, S., Fujita, M., Itokawa, H., Tanaka, O. and Ishii, T.: Studies on the constituents of Japanese and Chinese crude drugs. XI. Panaxadiol, a sapogenin of ginseng roots. Chem. Pharm. Bull. 11, 759-764 (1963) DOI ScienceOn |
12 | Austin, L.M., Ozawa, M., Kikuchi, T., Walters, I.B. and Krueger, J.G.: The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-r, interleukin-2, and tumor necrosis factor-a, defining Tc1 (cytotoxic T lymphocyte) and Th1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J. Invest. Dermatol. 113, 752-759 (1999) DOI ScienceOn |
13 | Nicoloff, B.J.: The cytokine network in psoriasis. Arch. Dermatol. 127, 871-884 (1991) DOI |
14 | Schafer-Korting, M., Schmid, M.H. and Korting, H.C.: Topical glucocorticoids with improved risk-benefit ratio. Rationale of a new concept. Drug Safety 14, 375-385 (1996) DOI ScienceOn |
15 | Wu, J.Y., Gardner, B.H., Murphy, C.I., Seals, J.R., Kensil, C.R., Recchia, J., Beltz, G.A., Newman, G.W. and Newman, M.J.: Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J. Immunol. 148, 1519-1525 (1992) |
16 | Choo, M.K., Park, E.K., Han, M.J. and Kim, D.H.: Antiallergic activity of ginseng and its ginsenoside. Planta Med. 69, 518-22 (2003) DOI ScienceOn |
17 | Hasegawa, H., Sung, J.H., Matsumiya, S. and Uchiyama, M.: Role of human intestinal Prevotella oris in hydrolyzing Ginseng saponis. Planta Med. 62, 453-457 (1996) DOI ScienceOn |
18 | Tawab, M.A., Bahr, U., Karas, M., Wurglics, M. and Schubert-Zsilavecz, M.: Degradation of ginsenosides in human after oral administration. Drug Metab. Dispos. 31, 1065-1071 (2003) DOI ScienceOn |
19 | Odani, T, Tanizawa, H. and Takino, Y.: Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. IV. Decomposition of ginsenoside-Rg1 and -Rb1 in the digestive tract of rats. Chem. Pharm. Bull. 31, 3691-3697 (1983) DOI ScienceOn |
20 | Shin, Y.W., Bae, E.A., Kim, S.S., Lee, Y.C., Lee, B.Y. and Kim, D.H.: The effects of ginsenoside Re and its metabolite, ginsenoside Rh1, on 12-O-tetradecanoylphorbol 13-acetateand oxazolone-induced mouse dermatitis models. Pland Med. 72, 376-378 (2006) DOI ScienceOn |