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http://dx.doi.org/10.5624/isd.2020.50.4.273

Several issues regarding the diagnostic imaging of medication-related osteonecrosis of the jaw  

Kim, Jo-Eun (Department of Oral and Maxillofacial Radiology, Seoul National University Dental Hospital)
Yoo, Sumin (School of Dental Hygiene, Kyungdong University Medical Campus)
Choi, Soon-Chul (Department of Oral and Maxillofacial Radiology, School of Dentistry, Seoul National University)
Publication Information
Imaging Science in Dentistry / v.50, no.4, 2020 , pp. 273-279 More about this Journal
Abstract
This review presents an overview of some diagnostic imaging-related issues regarding medication-related osteonecrosis of the jaws(MRONJ), including imaging signs that can predict MRONJ in patients taking antiresorptive drugs, the early imaging features of MRONJ, the relationship between the presence or absence of bone exposure and imaging features, and differences in imaging features by stage, between advanced MRONJ and conventional osteomyelitis, between oncologic and osteoporotic patients with MRONJ, and depending on the type of medication, method of administration, and duration of medication. The early diagnosis of MRONJ can be made by the presence of subtle imaging changes such as thickening of the lamina dura or cortical bone, not by the presence of bone exposure. Most of the imaging features are relatively non-specific, and each patient's clinical findings and history should be referenced. Oral and maxillofacial radiologists and dentists should closely monitor plain radiographs of patients taking antiresorptive/antiangiogenic drugs.
Keywords
Bisphosphonate-Associated Osteonecrosis of the Jaw; Radiography; Osteomyelitis; Radiography; Review;
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