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http://dx.doi.org/10.14478/ace.2021.1040

Recent Research Trend of Biosensors for Colorectal Cancer Specific Protein Biomarkers  

Li, Jingjing (Department of Chemistry, Kyungpook National University)
Si, Yunpei (Department of Chemistry, Kyungpook National University)
Lee, Hye Jin (Department of Chemistry, Kyungpook National University)
Publication Information
Applied Chemistry for Engineering / v.32, no.3, 2021 , pp. 253-259 More about this Journal
Abstract
Colorectal cancer (CRC) is one of the most prevalent diseases in modern society, constituting a serious threat to global health. Currently, routine clinical screening and early removal of precancerous polyps are the most successful methods for reducing CRC incidence and mortality. However, the high cost and invasive detection of sigmoidoscopy and colonoscopy limited the CRC-screening participation and prevention. The emergence of biosensors provides an inexpensive, sensitive, less invasive tool for detecting CRC disease biomarkers. This review highlights some of recent efforts made on developing biosensors with electrochemical and optical techniques targeting CRC specific protein biomarkers for early diagnosis and prognosis, potential applications, and future perspectives.
Keywords
Colorectal cancer; Protein biomarkers; Biosensors; Electrochemical methods; Optical techniques;
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