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http://dx.doi.org/10.14478/ace.2019.1024

Extraction of Antioxidants from Lonicera japonica and Sophora japonica L.: Optimization Using Central Composite Design Model  

Han, Kyongho (School of Electronics and Electrical Engineering, Dankook University)
Zuo, Chengliang (Department of Chemical Engineering, Dankook University)
Hong, In Kwon (Department of Chemical Engineering, Dankook University)
Publication Information
Applied Chemistry for Engineering / v.30, no.3, 2019 , pp. 337-344 More about this Journal
Abstract
In this study, an antioxidant was extracted from Lonicera japonica and Sophora japonica L, which was optimized by using the central composite design (CDD) model of response surface methodology (RSM). The response value of CDC model establishes the extraction yield and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. The extraction time, volume ratio of ethanol/ultrapure water, and extraction temperature were selected as quantitative factors. According to the result of CDC, optimal extraction conditions of Lonicera japonica were as follows; the extraction time of 2.08 h, volume ratio of ethanol/ultrapure water of 41.53 vol.%, and extraction temperature of $55.08^{\circ}C$. At these conditions the expected results indicated that the yield and DPPH radical scavenging activity were estimated as 37.88 wt% and 40.37%, respectively. On the other hand, optimal extraction conditions of Sophora japonica L. could be found as the extraction time of 2.13 h, volume ratio of ethanol/ultrapure water of 62.89 vol.%, and temperature of $50.42^{\circ}C$. Under the conditions, the (possible) maximum values of yield and DPPH radical scavenging activity were found as 35.43 wt% and 55.7%, respectively.
Keywords
Antioxidant; Lonicera japonica; Sophora japonica L.; Central composite design model;
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