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A Study on Entrapment Efficiency of Rosmarinic Acid Using Liquid Crystal Phosphatidylcholin  

Kang, Ki-Chun (Hanbul Cosmetics Co., R&D Center)
Publication Information
Applied Chemistry for Engineering / v.24, no.2, 2013 , pp. 132-137 More about this Journal
Abstract
The liquid crystal form with phosphatidylcholine contents containing in the hydrogenated lecithin was confirmed. Composition ingredients of the liquid crystal vesicle were phospholipid, ethanol and water and the rosmarinic acid was encapsulated as index material. The mean particle size of the liquid crystal vesicle appeared to form various particles form 480 nm to $3{\mu}m$ depending upon the lipid composition and ultrasonic handling time. The liquid crystal vesicle compared with the liposome showed a very high encapsulation efficiency. The quantity of liquid crystal vesicle increased with respect to the increased quantity of lipid contents in the hydrogenated lecithin. The result from release experiments of the liquid crystal vesicle containing rosmarinic acid showed that the liquid crystal vesicle releases much less than that of liposome.
Keywords
phosphatidylcholine; liquid crystal vesicle; hydrogenated lecithin; rosmarinic acid;
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