Browse > Article

A Study on N-Arylation of Indole Using Copper Nitrate or Copper Carbonate as a Catalyst  

Lee, Jun Young (Department of Chemical System Engineering, Keimyung University)
Yang, Min Ho (Department of Chemical System Engineering, Keimyung University)
Paik, Seung Uk (Department of Chemical System Engineering, Keimyung University)
Publication Information
Applied Chemistry for Engineering / v.19, no.6, 2008 , pp. 629-632 More about this Journal
Abstract
N-Arylation of indole with aryl iodides has been achieved by employing copper nitrate or copper cabonate as a catalyst, which might be more practical and economical over any other copper- or palladium-based catalysts for industrial applications. N,N'-dimethylethylenediamine was found to be the most effective with copper nitrate catalyst systems, while ethylenediamine was the most active with copper carbonate.
Keywords
arylation; copper nitrate; copper cabonate; indole;
Citations & Related Records

Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 F. He, B. M. Foxman, and B. B. Snider, J. Am. Chem. Soc., 120, 6417 (1998)   DOI   ScienceOn
2 A. Klapars, J. C. Antilla, X. Huang, and S. L. Buchward, J. Am. Chem. Soc., 123, 7727 (2001).   DOI   ScienceOn
3 J. C. Antilla and S. L. Buchwald, Org. Lett., 3, 2077 (2001)   DOI   ScienceOn
4 M. Sainsbury, Tetrahedron, 36, 3327 (1980)   DOI   ScienceOn
5 S. K. Kang, D. H. Kim, and J. N. Park, Synlett, 3, 427 (2002)
6 P. Lopez-Alvarado, C. Avandano, and J. C. Menendez, J. Org. Chem., 61, 5865 (1996)   DOI   ScienceOn
7 S.V. Ley, and A. W. Thomas, Angew. Chem. Int. Ed., 42, 5400 (2003)   DOI   ScienceOn
8 F. Ullmann, Ber. Dtsch. Chem. Ges. 36, 2382 (1903).   DOI
9 G. R. Martinez, K. A. M. Walker, D. R. Herschfield, J. J. Bruno, D. S. Yang, and P. J. Moloney, J. Med. Chem., 35, 620 (1992)   DOI
10 T. Manifar, S. Rohani, T. P. Bender, H. B. Goodbrand, R. Gaynor, and M. Saban, Ind. Eng. Chem. Res., 44, 789 (2005).   DOI   ScienceOn
11 G. I. Elliott and J. P. Konopelski, Org. Lett. 2, 3055 (2000)   DOI   ScienceOn
12 J. Hassan, M. Sevignon, C. Gozzi, E. Schulz, and M. Lemaire, Chem. Rev., 102, 1359 (2002)   DOI   ScienceOn
13 R. J. Sorenson, Org. Chem., 65, 7747 (2000)   DOI   ScienceOn
14 M. Wolter, A. Klapars, and S. L. Buchwald, Org. Lett., 3, 3803 (2001)   DOI   ScienceOn
15 H. M. Lee and S. P. Nolan, Org. Lett., 2, 2053 (2000)   DOI   ScienceOn