Browse > Article
http://dx.doi.org/10.7776/ASK.2022.41.5.557

Ultrasonic methods for measuring the cortical bone thickness in bovine tibia in vitro  

Lee, Kang Il (Department of Physics, Kangwon National University)
Publication Information
The Journal of the Acoustical Society of Korea / v.41, no.5, 2022 , pp. 557-563 More about this Journal
Abstract
The cortical bone thickness of the tibia is related to fracture risk and overall bone status. The present study aims to investigate the feasibility of two different ultrasonic methods for measuring the cortical bone thickness in bovine tibia in vitro. In the reflection technique, the tibial cortical thickness was determined from ultrasonic reflections from the periosteum and the endosteum producing specific peaks in the signal envelope. In the axial transmission technique, the tibial cortical thickness was determined from ultrasonic guided wave velocities measured along the axial direction of the tibia. The cortical bone thickness determined by using the reflection technique correlated significantly with that measured by using a caliper, with a Pearson's correlation coefficient of r = 0.97 (p < 0.0001). In contrast, the correlation coefficients for the axial transmission technique were r = 0.92 (p < 0.0001) for the first arriving signal method and r = 0.89 (p < 0.0001) for the slow guided wave method. Clinical feasibility should be demonstrated with an in vivo application to address the question whether the ultrasonic methods presented here could be useful as a screening tool for osteoporosis and potentially could be applied to other skeletal sites such as the femur and the radius.
Keywords
Quantitative ultrasound; Ultrasonic guided wave; Cortical bone; Cortical thickness; Bovine tibia;
Citations & Related Records
연도 인용수 순위
  • Reference
1 P. Laugier, "Instrumentation for in vivo ultrasonic characterization of bone strength," IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 55, 1179-1196 (2008).   DOI
2 J. A. Chen, J. Foiret, J. G. Minonzio, M. Talmant, Z. Q. Su, L. Cheng, and P. Laugier, "Measurement of guided mode wavenumbers in soft tissue-bone mimicking phantoms using ultrasonic axial transmission," Phys. Med. Biol. 57, 3025-3037 (2012).   DOI
3 H. Lamb, "On waves in an elastic plate," Proc. R. Soc. London A, 93, 114-128 (1917).   DOI
4 M. O. Culjat, D. Goldenberg, P. Tewari, and R. S. Singh, "A review of tissue substitutes for ultrasound imaging," Ultrasound Med. Biol. 36, 861-873 (2010).   DOI
5 S. P. Dodd, J. L. Cunningham, A. W. Miles, S. Gheduzzi, and V. F. Humphrey, "Ultrasonic propagation in cortical bone mimics," Phys. Med. Biol. 51, 4635-4647 (2006).   DOI
6 J. A. Kanis, E. V. McCloskey, H. Johansson, A. Oden, L. J. Melton III, and N. Khaltaev, "A reference standarad for the description of osteoporosis," Bone, 42, 467-475 (2008).   DOI
7 P. Moilanen, "Ultrasonic guided waves in bone," IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 55, 1277- 1286 (2008).   DOI
8 K. A. Wear, "Autocorrelation and cepstral methods for measurement of tibial cortical thickness," IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 50, 655-660 (2003).   DOI
9 J. Karjalainen, O. Riekkinen, J. Toyras, H. Kroger, and J. Jurvelin, "Ultrasonic assessment of cortical bone thickness in vitro and in vivo," IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 55, 2191-2197 (2008).   DOI
10 D. Hans and M. A. Krieg, "The clinical use of quantitative ultrasound (QUS) in the detection and management of osteoporosis," IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 55, 1529-1538 (2008).   DOI
11 P. Augat, H. Reeb, and L. E. Claes, "Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell," J. Bone Miner. Res. 11, 1356-1363 (1996).   DOI
12 P. H. F. Nicholson, P. Moilanen, T. Karkkainen, J. Timonen, and S. Cheng, "Guided ultrasonic waves in long bones: modelling, experiment and in vivo application," Physiol. Meas. 23, 755-768 (2002).   DOI