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http://dx.doi.org/10.4489/KJM.2010.39.3.189

Physiological Activities of Hot Water Extract and Solvent Fractions of Pleurotus ferulea  

Kim, Jun-Ho (Department of Fine Chemistry and New Materials, Sangji University)
Publication Information
The Korean Journal of Mycology / v.39, no.3, 2011 , pp. 189-193 More about this Journal
Abstract
To investigate the physiological activities of hot water extract and solvent fractions isolated from Pleurotus ferulea, antioxidative, fibrinolytic, thrombin inhibitory, and ${\alpha}$-glucosidase inhibitory activities were examined. Pleurotus ferulea, hot water extract was fractionated into hexane, chloroform, ethyl acetate, butanol and water fraction. Each of these was assayed individually. The antioxidative activities of ethyl acetate and butanol fractions were 86.79% and 87.82%, respectively. Using the fibrin plate method, only the ethyl acetate fraction showed a plasmin activity of 0.08 units/ml. Thrombin inhibitory activities of chloroform and ethyl acetate fractions were 74.90% and 71.08%, respectively. In the ${\alpha}$-glucosidase inhibitory activity test, butanol fraction showed the highest activity at 49.67%. From the above results, we anticipate that solvent fractions of Pleurotus ferulea can be used as a materials for the development of biofunctional foods for cardiovascular diseases.
Keywords
Antioxidative activity; Fibrinolytic activity; ${\alpha}$-Glucosidase inhibitory activity; Pleurotus ferulea; Thrombin inhibitory activity;
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Times Cited By KSCI : 6  (Citation Analysis)
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