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http://dx.doi.org/10.4489/KJM.2010.39.2.148

Stimulatory Effect of Cordyceps militaris on Testosterone Production in Male Mouse  

Hong, In-Pyo (National Academy of Agricultural Science, Rural Development Administration)
Choi, Yong-Soo (National Academy of Agricultural Science, Rural Development Administration)
Woo, Soon-Ok (National Academy of Agricultural Science, Rural Development Administration)
Han, Sang-Mi (National Academy of Agricultural Science, Rural Development Administration)
Kim, Hye-Kyung (National Academy of Agricultural Science, Rural Development Administration)
Lee, Myung-Ryul (National Academy of Agricultural Science, Rural Development Administration)
Nam, Sung-Hee (National Academy of Agricultural Science, Rural Development Administration)
Ha, Nam-Gyu (Environment-friendly Agriculture Research Division, Gyeongsangnam-do Agricultural Research & Extension Services)
Publication Information
The Korean Journal of Mycology / v.39, no.2, 2011 , pp. 148-150 More about this Journal
Abstract
Cordyceps militaris(CM) has been used as a traditional folk medicine to strengthen the immune system and regain energy for hundreds of years in Far East Asian countries. In the present studies, we determined that the stimulatory effect of Cordyceps militaris on testosterone production in male mouse rats. Results illustrated that changes of the body weight, food and water intake of the rats were not observed in this study but the concentration of testosterone in the serum of the rats was significantly increased by CM(p < 0.05). Therefore fruiting bodies of CM grown on the drone bee medium may be an integrative medicine for the treatment of reproductive problems caused by insufficient testosterone levels in human males.
Keywords
Cordyceps militaris; Drone; Testosterone;
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1 Chang, Y., Jeng, K. C., Huang, K. F., Lee, Y. C., Hou, C., W., Chen, K. H., Cheng, F. Y., Liao, J. W. and Chen, Y. S. 2008. Effect of Cordyceps militaris supplementation on sperm production, sperm motility and hormones in Sprague-Dewley rats. Am. J. Chin. Med. 36:849-859.   DOI   ScienceOn
2 Choi, Y. S., Lee, M. L., Lee, M. Y., Kim, H. K., Lee, K. G., Yeo, J. H. and Woo, S. O. 2009. Maanagement for high quality drone products. Korean J. Apiculture 24:1-7.
3 Crimmel, A. S., Conner, C. S. and Monga, M. 2001. Withered Yang: a review of traditional Chinese medical treatment of male infertility and erectile dysfunction. Journal of Andrology 22:173-182.
4 Veal, L. 1998. Complementary therapy and infertility: an Icelandic perspective Complement. Therapies in Nursing and Midwifery 4:3-6.   DOI   ScienceOn
5 Huang, Y.L., Leu, S. F., Liu, B. C., Sheu, C. C. and Huang, B.M. 2004. In vivo stimulatory effects of Cordyceps sinensis mycelium and its fractions on reproductive functions in male mouse. Life Sciences 75:1051-1062.   DOI   ScienceOn
6 Ng, T. B. and Wang, H. X. 2005. Pharmacological actions of cordyceps, a prized folk medicine. J. pharm. pharmacol. 57:1509-1519.   DOI   ScienceOn
7 Rege, N. N., Date, J., Kulkarni, V., Prem, A.R., Punekar, S.V. and Dahanukar, S.A. 1997. Effect of Y virilin on male infertility. Journal of Postgraduate Medicine 43:64-67.
8 Saez, J.M. 1994. Leydig cells: endocrine, paracrine and autocrine regulation. Endocrine Review 15:574-626.   DOI
9 In-Pyo Hong, I. P., Lee, M. Y., Choi, Y. S., Kim, H. K., Lee, K. G., Humber, R. A. and Guo, S. X. 2010. Fruiting body formation of Cordyceps militaris using Bee Drone. Journal of Apiculture 25:229-234.
10 Hsu, C.C., Huang, Y.L., Tsai, S.C., Sheu, C.C. and Huang, B.M. 2003. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sciences 73:2127-2136.   DOI   ScienceOn