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http://dx.doi.org/10.4489/KJM.2005.33.2.064

Effects of Inonotus obliquus Mycelia on the Level of Plasma Glucose and Lipids in Streptozotocin-induced Diabetic Rats  

Yang, Byung-Keun (Department of Biotechnology, Daegu University)
Cho, Kai-Yip (School of Science, Food & Horticulture, University of Western Sydney)
Wilson, Michael A. (School of Science, Food & Horticulture, University of Western Sydney)
Song, Chi-Hyun (Department of Biotechnology, Daegu University)
Publication Information
The Korean Journal of Mycology / v.33, no.2, 2005 , pp. 64-68 More about this Journal
Abstract
This investigation was undertaken to study the effects of oral administration of Inonotus obliquus mycelia produced by a submerged culture on plasma glucose level and other biochemical parameters in streptozotocin (STZ)-induced diabetic rats. The mycelia, at the dose of 200 mg/kg body weight (BW), substantially reduced the plasma glucose level by as much as 23.1% as compared to the control group. The levels of total cholesterol and triglyceride in plasma were reduced to the extent of 12.6% and 22.6%, respectively. The activities of alanine transaminase (ALT) and aspartate transaminase (AST) were decreased by 27.6% and 21.9%, respectively, under the influence of I. obliquus mycelia. The general components of I. obliquus mycelia were found to contain 5.55% crude ash, 2.35% crude fat, 28.29% crude protein, 9.53% carbohydrate, and 54.28% dietary fiber.
Keywords
Diabetic rats; Glucose; Inonotus obliquus mycelia; Submerged culture;
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Times Cited By KSCI : 7  (Citation Analysis)
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