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http://dx.doi.org/10.4489/KJM.2002.30.2.131

Production of Lentinus edodes Mycelia in Submerged Culture and It's Hypoglycemic Effect in Diabetic Rats  

Yang, Byung-Keun (Research Center for Processing & Application of Agricultural Products, Taegu University)
Kim, Dong-Hyun (Department of Biotechnology, Taegu University)
Song, Chi-Hyun (Department of Biotechnology, Taegu University)
Publication Information
The Korean Journal of Mycology / v.30, no.2, 2002 , pp. 131-135 More about this Journal
Abstract
The optimum conditions for the production of Lentinus edodes mycelia and it's hypoglycemic effect was studied. Optimum pH and temperature for the production of mycelia in shaken flask culture were 5 and $30^{\circ}C$, respectively, for 24 days cultivation. Culture period for maximum production of mycelia (8.13 g/l) in 5-l jar fermenter cultivation was shortened as much as 6 days compared to shaken flask culture. The mycelial dose of 5 % proved almost equally effective in lowering the plasma glucose, total cholesterol, and triglyceride level as much as 23.0, 20.7, and 27.1%, respectively. The values of alanine transaminase and aspartate transaminase were also estimated and exhibited a substantial reduction (29.6 and 34.3%, respectively) in activity after the administration of dried mycelia.
Keywords
Hypoglycemic effect; Lentinus edodes mycelia; Submerged culture;
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Times Cited By KSCI : 3  (Citation Analysis)
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