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http://dx.doi.org/10.6111/JKCGCT.2012.22.2.092

Bioactivity behavior of Si and Mg ion-substituted biphasic calcium phosphate powders  

Kim, Tae-Wan (School of Materials Science Engineering, Pusan National University)
Kim, Dong-Hyun (School of Materials Science Engineering, Pusan National University)
Jin, Hyeong-Ho (School of Materials Science Engineering, Pusan National University)
Lee, Heon-Soo (Division of Electrical and Electronic Engineering, Daegu Technical University)
Park, Hong-Chae (School of Materials Science Engineering, Pusan National University)
Yoon, Seog-Young (School of Materials Science Engineering, Pusan National University)
Publication Information
Journal of the Korean Crystal Growth and Crystal Technology / v.22, no.2, 2012 , pp. 92-98 More about this Journal
Abstract
The co-precipitation technique has been applied to synthesize biphasic calcium phosphate (BCP). $Ca(NO_3)_2{\cdot}4H_2O$, $(NH_4)_2HPO_4$, TEOS and $Mg(NO_3)_2{\cdot}6H_2O$ as the starting materials was used. After the heat treatment of powder crystalline phases HAp and ${\beta}$-TCP analysis showed a mixed phase. The overall spectra appear to have mainly two modes corresponding to characteristic $PO^{3-}_4$ and $OH^-$ groups. After immersion in Hanks' Balanced Salt Solution (HBSS) for 1 week a precipitation started to be formed with individual small granules on the specimen surface. An MTT assay indicated that ionic substituted BCP powders had no cytotoxic effects on MG-63 cells, and that they have good biocompatibility.
Keywords
Biphasic calcium phosphate; Silicon; Magnesium; Co-precipitation;
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