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Bioactive Constituents and Utilities of Ganghwayakssuk (Artemisia princeps Pamp.)  

Ryu, Su-Noh (Dept. of Agricultural Sci, Korea Nat'l Open Univ.)
Publication Information
Journal of the Korean Society of International Agriculture / v.20, no.4, 2008 , pp. 308-314 More about this Journal
Abstract
The Artemisia which is widely distributed with many and various among the Asteraceae, is currently reported existing about 400 different species. These are mainly distributed over the Northern hemi-sphere comprising Asisa, Europe, North America. The Ganghwayakssuk is divided into two classes such as the Sajabalssuk and the Ssajuarissuk. These two classes are indistinguishable from each other with general characteristics beside leaves. Moreover, the characteristics of leaves also show continuous variation based on two types. As a result of analysis on the morphological characteristics and the principle component of leaves, the Sajabalssuk has been reported as another type of the Ssajuarissuk. There are many medicinal constituents identified from the Genus Artemisia, for example, flavonoids, such as eupatilin, jaceosidin, eupafolin, apigenin, hispidulin etc., phenylpropanoids such as 9-hydroxyeugenol, sesamin, ursolic acid etc., and triterpenoids such as wrightial, wrightial acetate, ursolic acid, amyrin acetate, cycloartanol etc. It is identified that alcohol extracts of the Ganghwayakssuk have effect on improving symptoms type II diabetes, hyperlipidemia, hypertention etc. In addition, with regarding to anti-cancer activities, the Artemisia induced apoptosis and reduced nephrotoxicity that is induced by the medication of anti-cancer drug. Alcohol extracts of the Ganghwayakssuk also are known to have effects on inhibiting obesity and improving liver function and atopicallergy via the antiinflammatory and anti-allergic efficacy. Accordingly, there are many potentials to develop health care foods, medicines, cosmedicals etc. with the Ganghwayakssuk, as it contains various constituents showing medicinal activities.
Keywords
Artemisia princeps; bioactive; eupatilin; jaceosidin; eupafolin; apigenin; hispidulin
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