A prestressed concrete slab bridge is analyzed by the specially orthotropic laminates theory. Both the geometry and the material of the cross section of the slab are considered symmetrical with respect to the mid-surface so that the bending extension coupling stiffness, , and . Each longitudinal and transverse steel layer is regarded as a lamina, and material constants of each lamina is calculated by the use of rule of mixture. This bridge with simple support is under uniformly distributed vertical and axial loads. In this paper, the finite difference method and the beam theory are used for analysis. The result of beam analysis is modified to obtain the solution of the plate analysis.