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http://dx.doi.org/10.17703/JCCT.2019.05.2.397

The Anti-inflammatory Effects of Heat-treated Broccoli Extract  

Kim, Hyun Kyoung (Dept. of Food Science and Enginerring, Seowon Univ)
Publication Information
The Journal of the Convergence on Culture Technology / v.5, no.2, 2019 , pp. 397-404 More about this Journal
Abstract
This study was carried out to investigate the heat-treated broccoli extraction which have a beneficial effect on the human body and which can be used safely for a long period of time without adverse side effects and also have excellent effects of protecting liver and improving liver function. The heat-treated broccoli extract does not show cytotoxicity, and thus can be used safely. In an experiment performed on an animal model with liver injury induced by a drug (APAP), it could be seen that the heat-treated cabbage extract exhibited the effects of protecting liver and improving liver function by effectively reducing AST and ALT which are liver injury markers, indicating that the heat-treated brocoli extract is effective as a pharmaceutical extraction for preventing or treating liver disease. In particular, the heat-treated broccoli extract was effective in treating inflammation of the liver by reducing the expression of the inflammatory mediators iNOS and COX-2 and the proinflammatory cytokine $IL-1{\beta}$, which are involved in acute inflammatory reactions accompanying liver injury.
Keywords
Broccoli; Anti-inflammatory; Protecting liver; Improving liver function; Side effects;
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Times Cited By KSCI : 2  (Citation Analysis)
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