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http://dx.doi.org/10.17703/JCCT.2019.5.2.389

The Effects of Protecting Liver and Improving Liver Function on Cabbage Extract  

Kim, Hyun Kyoung (Dept. of Food Science and Enginerring, Seowon Univ.)
Publication Information
The Journal of the Convergence on Culture Technology / v.5, no.2, 2019 , pp. 389-395 More about this Journal
Abstract
This study investigated the pharmaceutical extraction and the functional health food extraction, which have a beneficial effect on the human body and which can be used safely for a long period of time without adverse side effects and also have excellent effects of protecting liver and improving liver function. As the results, the cabbage extract does not show cytotoxicity, and thus can be used safely. In an experiment performed on an animal model with liver injury induced by a drug (APAP), it could be seen that the cabbage extract exhibited the effects of protecting liver and improving liver function by effectively reducing AST and ALT which are liver injury markers, indicating that the cabbage extract is effective as a pharmaceutical extraction for preventing or treating liver disease. In particular, the cabbage extract was effective in treating inflammation of the liver by reducing the expression of the inflammatory mediators iNOS and COX-2 and the proinflammatory cytokine $IL-1{\beta}$, which are involved in acute inflammatory reactions accompanying liver injury. In the results, an extract of cabbage heat-treated at a temperature of 100 to $150^{\circ}C$ had a better liver function-improving effect or anti-inflammatory effect than an extract of raw cabbage.
Keywords
Cabbage; Hepatoprotective activity; Anti-inflammatory; Liver disease; Cytotoxicity;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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