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http://dx.doi.org/10.7735/ksmte.2013.22.2.235

Disposable Microfluidic Infusion Pump using Elastomeric Blister Actuator  

Jang, Woong Ki (강원대학교 기계메카트로닉스공학과 대학원)
Kim, Hyung Jin (강원대학교 기계메카트로닉스공학과 대학원)
Kim, Byeong Hee (강원대학교 기계메카트로닉스공학과)
Seo, Young Ho (강원대학교 기계메카트로닉스공학과 대학원)
Publication Information
Journal of the Korean Society of Manufacturing Technology Engineers / v.22, no.2, 2013 , pp. 235-240 More about this Journal
Abstract
This paper presents a disposable microfluidic infusion pump using the restoring force of elastomeric membrane of Polydimethylsiloxane. Microfluidic infusion pump consists of hydraulic resistance control part, elastomeric blister actuator part, drug inlet and outlet. Expanded elastomeric blister actuator continuously pushes liquid in the chamber to outlet. At same time, microchannel diameter near the outlet was controlled by thin elastomeric membrane in hydraulic resistance control part. Eventually flow rate of infused liquid is controlled by air pressure. In experimental study, the amount of the filled liquid in the blister is precisely controlled by the height of the blister. Flow rate of infused liquid could be controlled, that is, controlled release of the drug over time was possible by adjusting hydraulic resistance and restoring pressure with the blister actuator.
Keywords
Disposable microfluidic pump; Elastomeric blister actuator;
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