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http://dx.doi.org/10.4046/trd.2017.80.1.21

Preventing the Transmission of Tuberculosis in Health Care Settings: Administrative Control  

Jo, Kyung-Wook (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.80, no.1, 2017 , pp. 21-26 More about this Journal
Abstract
It is well established that health care workers (HCWs) have a considerably higher risk of occupationally acquired tuberculosis (TB). To reduce the transmission of TB to HCWs and patients, TB infection control programs should be implemented in health care settings. The first and most important level of all protection and control programs is administrative control. Its goals are to prevent HCWs, other staff, and patients from being exposed to TB, and to reduce the transmission of infection by ensuring rapid diagnosis and treatment of affected individuals. Administrative control measures recommended by the United States Centers for Disease Control and Prevention and the World Health Organization include prompt identification of people with TB symptoms, isolation of infectious patients, control of the spread of the pathogen, and minimization of time spent in health care facilities. Another key component of measures undertaken is the baseline and serial screening for latent TB infection in HCWs who are at risk of exposure to TB. Although the interferon-gamma release assay has some advantages over the tuberculin skin test, the former has serious limitations, mostly due to its high conversion rate.
Keywords
Tuberculosis; Health Personnel; Tuberculin Test; Interferon-Gamma Release Tests;
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1 Dorman SE, Belknap R, Graviss EA, Reves R, Schluger N, Weinfurter P, et al. Interferon-gamma release assays and tuberculin skin testing for diagnosis of latent tuberculosis infection in healthcare workers in the United States. Am J Respir Crit Care Med 2014;189:77-87.
2 Park JS, Lee JS, Kim MY, Lee CH, Yoon HI, Lee SM, et al. Monthly follow-ups of interferon-gamma release assays among health-care workers in contact with patients with TB. Chest 2012;142:1461-8.   DOI
3 Metcalfe JZ, Cattamanchi A, McCulloch CE, Lew JD, Ha NP, Graviss EA. Test variability of the QuantiFERON-TB gold intube assay in clinical practice. Am J Respir Crit Care Med 2013;187:206-11.   DOI
4 King TC, Upfal M, Gottlieb A, Adamo P, Bernacki E, Kadlecek CP, et al. T-SPOT.TB interferon-gamma release assay performance in healthcare worker screening at nineteen U.S. hospitals. Am J Respir Crit Care Med 2015;192:367-73.   DOI
5 Jensen PA, Lambert LA, Iademarco MF, Ridzon R; CDC. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005. MMWR Recomm Rep 2005;54:1-141.
6 Verkuijl S, Middelkoop K. Protecting our front-liners: occupational tuberculosis prevention through infection control strategies. Clin Infect Dis 2016;62 Suppl 3:S231-7.   DOI
7 Centers for Disease Control and Prevention. Core curriculum on tuberculosis: what the clinicians should know [Internet]. Atlanta: Centers for Disease Control and Prevention; 2013 [cited 2016 Sep 1]. Available from: http://www.cdc.gov/tb/education/corecurr/pdf/corecurr_all.pdf.
8 World Health Organization. WHO policy on TB infection control in health-care facilities, congregate settings and households [Internet]. Geneva: World Health Organization; 2009 [cited 2016 Sep 1]. Available from: http://www.who.int/publications/guidelines/en/.
9 Pai M, Kunimoto D, Jamieson F, Menzies D. Canadian tuberculsosis standards, 7th edition. Diagnosis latent tuberculosis infection. Can Respir J 2013;20(Suppl A):23A-34A.   DOI
10 Institute of Medicine (US) Committee on the Elimination of Tuberculosis in the United States; Geiter L. Ending neglect: the elimination of tuberculosis in the United States. Washington, DC: National Academy Press; 2000.
11 Meredith S, Watson JM, Citron KM, Cockcroft A, Darbyshire JH. Are healthcare workers in England and Wales at increased risk of tuberculosis? BMJ 1996;313:522-5.   DOI
12 Chu H, Shih CJ, Lee YJ, Kuo SC, Hsu YT, Ou SM, et al. Risk of tuberculosis among healthcare workers in an intermediateburden country: a nationwide population study. J Infect 2014;69:525-32.   DOI
13 Jo KW, Woo JH, Hong Y, Choi CM, Oh YM, Lee SD, et al. Incidence of tuberculosis among health care workers at a private university hospital in South Korea. Int J Tuberc Lung Dis 2008;12:436-40.
14 Menzies D, Joshi R, Pai M. Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007;11:593-605.
15 Clinical practice guideline for tuberculosis [Internet]. Clinical Practice Guidelines Committee; 2011 [cited 2016 Sep 1]. Available from: http://www.lungkorea.org/image/mail/file_110217.pdf.
16 Casas I, Esteve M, Guerola R, Garcia-Olive I, Roldan-Merino J, Martinez-Rivera C, et al. Incidence of tuberculosis infection among healthcare workers: risk factors and 20-year evolution. Respir Med 2013;107:601-7.   DOI
17 Lee K, Han MK, Choi HR, Choi CM, Oh YM, Lee SD, et al. Annual incidence of latent tuberculosis infection among newly employed nurses at a tertiary care university hospital. Infect Control Hosp Epidemiol 2009;30:1218-22.   DOI
18 Sutherland I. Recent studies in the epidemiology of tuberculosis, based on the risk of being infected with tubercle bacilli. Adv Tuberc Res 1976;19:1-63.
19 Sutherland I. The evolution of clinical tuberculosis in adolescents. Tuberculosis 1966;47:308.
20 Lobue P, Menzies D. Treatment of latent tuberculosis infection: an update. Respirology 2010;15:603-22.   DOI
21 Targeted tuberculin testing and treatment of latent tuberculosis infection. American Thoracic Society. MMWR Recomm Rep 2000;49:1-51.
22 Snider DE Jr, Cauthen GM. Tuberculin skin testing of hospital employees: infection, "boosting," and two-step testing. Am J Infect Control 1984;12:305-11.   DOI
23 Kim SY, Park MS, Kim YS, Kim SK, Chang J, Yong D, et al. Tuberculin skin test and boosted reactions among newly employed healthcare workers: an observational study. PLoS One 2013;8:e64563.   DOI
24 Fong KS, Tomford JW, Teixeira L, Fraser TG, van Duin D, Yen-Lieberman B, et al. Challenges of interferon-gamma release assay conversions in serial testing of health-care workers in a TB control program. Chest 2012;142:55-62.   DOI
25 Slater ML, Welland G, Pai M, Parsonnet J, Banaei N. Challenges with QuantiFERON-TB Gold assay for large-scale, routine screening of U.S. healthcare workers. Am J Respir Crit Care Med 2013;188:1005-10.   DOI