Browse > Article
http://dx.doi.org/10.4046/trd.2016.79.3.184

IgG4-Related Lung Disease without Elevation of Serum IgG4 Level: A Case Report  

Kang, Min Kyu (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Cho, Yongseon (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Han, Minsoo (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Jung, Sun Young (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Moon, Kyoung Min (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Kim, Jinyoung (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Kim, Ju Ri (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Lee, Dong-kyu (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Park, Jun Hyung (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Chung, So Hee (Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital)
Publication Information
Tuberculosis and Respiratory Diseases / v.79, no.3, 2016 , pp. 184-187 More about this Journal
Abstract
Since IgG4-related pancreatitis was first reported in 2001, IgG4-related disease has been identified in other organs such as salivary gland, gallbladder, thyroid, retroperitoneum and kidney; but lung invasion is rare. A 63-year-old man presented with hemoptysis at the pulmonary clinic and chest computed tomography revealed about 4.1 cm irregular shaped mass with spiculated margin at the left upper lobe. Despite no elevation of serum IgG4 level, he was finally diagnosed as IgG4-related lung disease by transthoracic needle biopsy. After treatment with oral glucocorticoids, hemoptysis disappeared and the size of lung mass was decreased.
Keywords
Immunoglobulins; Lung Diseases; Hemoptysis;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 Stone JH, Zen Y, Deshpande V. IgG4-related disease. N Engl J Med 2012;366:539-51.   DOI
2 Kamisawa T, Funata N, Hayashi Y, Eishi Y, Koike M, Tsuruta K, et al. A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol 2003;38:982-4.   DOI
3 Zen Y, Inoue D, Kitao A, Onodera M, Abo H, Miyayama S, et al. IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases. Am J Surg Pathol 2009;33:1886-93.   DOI
4 Inoue D, Zen Y, Abo H, Gabata T, Demachi H, Kobayashi T, et al. Immunoglobulin G4-related lung disease: CT findings with pathologic correlations. Radiology 2009;251:260-70.   DOI
5 Hamano H, Kawa S, Horiuchi A, Unno H, Furuya N, Akamatsu T, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med 2001;344:732-8.   DOI
6 Yoo JW, Roh JH, Lim CM, Lee SD, Kim WS, Kim DS, et al. Two cases of pulmonary involvement of immunoglobulin G4 related autoimmune disease. Tuberc Respir Dis 2009;67:359-63.   DOI
7 Kwon SH, Lee YK, Shim MS, Lee HI. A case of immunoglobulin G4-related sclerosing disease mimicking lung cancer. J Korean Soc Radiol 2013;69:53-6.   DOI
8 Park HY, Han J, Kang G, Yi CA, Chung MP. IgG4-related lung disease presenting as a consolidative mass: a case report. J Lung Cancer 2010;9:103-5.   DOI
9 Kim DH, Koh KH, Oh HS, Kim SJ, Kang SH, Jung BW, et al. A case of immunoglobulin g4-related disease presenting as a pleural mass. Tuberc Respir Dis 2014;76:38-41.   DOI
10 Choi IH, Jang SH, Lee S, Han J, Kim TS, Chung MP. A case report of IgG4-related disease clinically mimicking pleural mesothelioma. Tuberc Respir Dis 2014;76:42-5.   DOI
11 Choi JH, Sim JK, Oh JY, Lee EJ, Hur GY, Lee SH, et al. A case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis. Tuberc Respir Dis 2014;76:179-83.   DOI
12 Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, et al. Consensus statement on the pathology of IgG4-related disease. Mod Pathol 2012;25:1181-92.   DOI
13 Ahn JH, Hong SI, Cho DH, Chae EJ, Song JS, Song JW. A case of IgG4-related lung disease presenting as interstitial lung disease. Tuberc Respir Dis 2014;77:85-9.   DOI
14 Kim WJ, Kim YI, Kim JE, Choi YH, Cho HH, Choi YD, et al. Unexplained persistent dyspnea in a young woman with eosinophilic angiocentric fibrosis. Respir Care 2014;59:e72-6.   DOI
15 Ost D, Fein AM, Feinsilver SH. Clinical practice: the solitary pulmonary nodule. N Engl J Med 2003;348:2535-42.   DOI