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http://dx.doi.org/10.4046/trd.2016.79.1.37

Severe Endobronchial Inflammation Induced by Aspiration of a Ferrous Sulfate Tablet  

Lim, Sang Youn (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Sohn, Sung Birm (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Lee, Jung Min (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Lee, Ji Ae (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Chung, Sangmi (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Kim, Junga (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Choi, Juwhan (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Kim, Sehwa (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Yoo, Ah Young (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Roh, Jong Ah (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Park, Haein (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Kim, Won Shik (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Sim, Jae Kyeom (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Shim, Jae Jeong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Min, Kyung Hoon (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School)
Publication Information
Tuberculosis and Respiratory Diseases / v.79, no.1, 2016 , pp. 37-41 More about this Journal
Abstract
Iron supplements such as ferrous sulfate tablets are usually used to treat iron-deficiency anemia in some elderly patients with primary neurologic disorders or decreased gag reflexes due to stroke, senile dementia, or parkinsonism. While the aspiration of ferrous sulfate is rarely reported, it is a potentially life-threatening condition that can lead to airway necrosis and bronchial stenosis. A detailed history and high suspicion of aspiration are required to avoid delays in diagnosis and treatment. The diagnosis can be confirmed by bronchoscopic examination and a tissue biopsy. Early removal of the aspirated tablet prevents acute complications, such as bronchial necrosis, hemoptysis, and lobar consolidation. Tablet removal is also necessary to prevent late bronchial stenosis. We presented the first case in Korea of a ferrous sulfate tablet aspiration that induced severe endobronchial inflammation.
Keywords
Foreign Bodies; Respiratory Aspiration; Bronchi; Bronchoscopy;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Baharloo F, Veyckemans F, Francis C, Biettlot MP, Rodenstein DO. Tracheobronchial foreign bodies: presentation and management in children and adults. Chest 1999;115:1357-62.
2 Lamaze R, Trechot P, Martinet Y. Bronchial necrosis and granuloma induced by the aspiration of a tablet of ferrous sulphate. Eur Respir J 1994;7:1710-1.   DOI
3 Boyd M, Watkins F, Singh S, Haponik E, Chatterjee A, Conforti J, et al. Prevalence of flexible bronchoscopic removal of foreign bodies in the advanced elderly. Age Ageing 2009;38:396-400.   DOI
4 Lee JO, Lee JH, Ahn S, Kim JW, Chang H, Kim YJ, et al. Prevalence and risk factors for iron deficiency anemia in the korean population: results of the fifth KoreaNational Health and Nutrition Examination Survey. J Korean Med Sci 2014;29:224-9.   DOI
5 Mahmood K, Koubar S, Shofer SL, Ninan NA, Wahidi MM. Alendronate tracheobronchitis. Ann Am Thorac Soc 2013;10:64-6.   DOI
6 Sundar KM, Elliott CG, Thomsen GE. Tetracycline aspiration: case report and review of the literature. Respiration 2001;68:416-9.   DOI
7 Karakan Y, Akpinar A, Yildiz H, Aksoy H, Dikensoy O. A case of ciprofloxacin tablet aspiration. Tuberk Toraks 2010;58:97-9.
8 Micallef J, Montefort S, Mallia Azzopardi C, Galea J. Two cases of aspiration of calcium tablets. Lung India 2011;28:312-4.   DOI
9 Radiological notes: aspirated capsule in right lower lobe. J Mt Sinai Hosp N Y 1966;33:530-2.
10 Cimino-Mathews A, Illei PB. Cytologic and histologic findings of iron pill-induced injury of the lower respiratory tract. Diagn Cytopathol 2013;41:901-3.
11 Maw M, Chiu R, Lim AY. Bronchoscopic and histological changes over time following acute ferrous sulphate tablet aspiration. BMJ Case Rep 2012;2012:bcr2012007329.
12 Venci NM, Watson TJ, Kallay MC. Bronchial stenosis following ferrous sulfate aspiration: case report and review of the literature. J Bronchology Interv Pulmonol 2014;21:58-60.   DOI
13 Ceylan N, Bayraktaroglu S, Savas R, Alper H. CT findings of high-attenuation pulmonary abnormalities. Insights Imaging 2010;1:287-92.   DOI
14 Lee P, Culver DA, Farver C, Mehta AC. Syndrome of iron pill aspiration. Chest 2002;121:1355-7.   DOI
15 Kim ST, Kaisar OM, Clarke BE, Vandenburg RA, Allen DH, Bell SC, et al. 'Iron lung': distinctive bronchoscopic features of acute iron tablet aspiration. Respirology 2003;8:541-3.   DOI