[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.4046/trd.2015.78.3.227

Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013

Ahn, Bin (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)
Kim, Joohae (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)
Yoo, Chul-Gyu (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)
Kim, Young Whan (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)
Han, Sung Koo (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)
Yim, Jae-Joon (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine)

Publication Information

Tuberculosis and Respiratory Diseases / v.78, no.3, 2015 , pp. 227-231 More about this Journal

Abstract

Background: Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden. Methods: Patients diagnosed with pulmonary TB in the first halves of 2005 and 2013 at a tertiary referral hospital were included. Diagnostic methods that prompted the initiation of anti-TB treatment were compared between the 2 groups of patients. Results: A greater proportion of patients were diagnosed with pulmonary TB using bronchoscopy in 2013 than in 2005 (26.7% vs. 6.6%, respectively; p<0.001), while the proportion of patients clinically diagnosed with pulmonary TB was lower in 2013 than in 2005 (24.7% vs. 49.0%, respectively; p<0.001). Additionally, more patients started anti-TB treatment based on positive polymerase chain reaction (PCR) results for Mycobacterium tuberculosis DNA in 2013 than in 2005 (47.3% vs. 7.9%, respectively; p<0.001). Conclusion: The initiation of treatment for pulmonary TB in South Korea has become more frequently based on PCR and the use of bronchoscopic specimens.

Keywords

Tuberculosis; Pulmonary; Diagnosis; Bronchoscopy; Nucleic Acid Amplification Techniques;

Citations & Related Records

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