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http://dx.doi.org/10.4046/trd.2014.77.3.141

Fatal Clinical Course of Probable Invasive Pulmonary Aspergillosis with Influenza B Infection in an Immunocompetent Patient  

Park, Dong Won (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Yhi, Ji Young (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Koo, Gunwoo (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Jung, Sung Jun (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Kwak, Hyun Jung (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Moon, Ji-Yong (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Kim, Sang-Heon (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Kim, Tae Hyung (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Sohn, Jang Won (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Shin, Dong Ho (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Park, Sung Soo (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Yoon, Ho Joo (Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.77, no.3, 2014 , pp. 141-144 More about this Journal
Abstract
Invasive pulmonary aspergillosis (IPA) is rarely reported in patients who have normal immune function. Recently, IPA risk was reported in nonimmunocompromised hosts, such as patients with chronic obstructive pulmonary disease and critically ill patients in intensive care units. Moreover, influenza infection is also believed to be associated with IPA among immunocompetent patients. However, most reports on IPA with influenza A infection, including pandemic influenza H1N1, and IPA associated with influenza B infection were scarcely reported. Here, we report probable IPA with a fatal clinical course in an immunocompetent patient with influenza B infection. We demonstrate IPA as a possible complication in immunocompetent patients with influenza B infection. Early clinical suspicion of IPA and timely antifungal therapy are required for better outcomes in such cases.
Keywords
Invasive Pulmonary Aspergillosis; Influenza B Virus; Immunocompetence;
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1 De Pauw B, Walsh TJ, Donnelly JP, Stevens DA, Edwards JE, Calandra T, et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 2008;46:1813-21.   DOI   ScienceOn
2 Meersseman W, Lagrou K, Maertens J, Van Wijngaerden E. Invasive aspergillosis in the intensive care unit. Clin Infect Dis 2007;45:205-16.   DOI
3 Trof RJ, Beishuizen A, Debets-Ossenkopp YJ, Girbes AR, Groeneveld AB. Management of invasive pulmonary aspergillosis in non-neutropenic critically ill patients. Intensive Care Med 2007;33:1694-703.   DOI   ScienceOn
4 Stevens DA, Melikian GL. Aspergillosis in the 'nonimmunocompromised' host. Immunol Invest 2011;40:751-66.   DOI
5 Clancy CJ, Nguyen MH. Acute community-acquired pneumonia due to Aspergillus in presumably immunocompetent hosts: clues for recognition of a rare but fatal disease. Chest 1998;114:629-34.   DOI   ScienceOn
6 Lat A, Bhadelia N, Miko B, Furuya EY, Thompson GR 3rd. Invasive aspergillosis after pandemic (H1N1) 2009. Emerg Infect Dis 2010;16:971-3.   DOI
7 Wauters J, Baar I, Meersseman P, Meersseman W, Dams K, De Paep R, et al. Invasive pulmonary aspergillosis is a frequent complication of critically ill H1N1 patients: a retrospective study. Intensive Care Med 2012;38:1761-8.   DOI   ScienceOn
8 Kwon OK, Lee MG, Kim HS, Park MS, Kwak KM, Park SY. Invasive pulmonary aspergillosis after influenza a infection in an immunocompetent patient. Tuberc Respir Dis 2013;75:260-3.   DOI
9 Hasejima N, Yamato K, Takezawa S, Kobayashi H, Kadoyama C. Invasive pulmonary aspergillosis associated with influenza B. Respirology 2005;10:116-9.   DOI   ScienceOn
10 Ohnishi T, Andou K, Kusumoto S, Sugiyama H, Hosaka T, Ishida H, et al. Two cases of successfully treated invasive pulmonary aspergillosis following influenza virus infection. Nihon Kokyuki Gakkai Zasshi 2007;45:349-55.
11 Labella AM, Merel SE. Influenza. Med Clin North Am 2013;97: 621-45.   DOI
12 Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2008;46:327-60.   DOI   ScienceOn
13 Hope WW, Walsh TJ, Denning DW. Laboratory diagnosis of invasive aspergillosis. Lancet Infect Dis 2005;5:609-22.   DOI   ScienceOn
14 Herbrecht R, Denning DW, Patterson TF, Bennett JE, Greene RE, Oestmann JW, et al. Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med 2002;347:408-15.   DOI   ScienceOn