Browse > Article
http://dx.doi.org/10.4046/trd.2013.75.5.218

Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis  

Yeo, Hye Ju (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Lee, Soo Yong (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Ahn, Eunyoung (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Kim, Eun Jung (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Rhu, Dae Gon (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Choi, Kyoung Un (Department of Pathology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Lee, Seung Eun (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Cho, Woo Hyun (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Jeon, Doosoo (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Kim, Yun Seong (Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.75, no.5, 2013 , pp. 218-221 More about this Journal
Abstract
This report describes a rare case of a patient with splenic tuberculosis (TB) who developed spontaneous splenic rupture after 10 weeks of antituberculous chemotherapy. The patient responded well to the antituberculous regimen prior to the spontaneous splenic rupture. We considered a paradoxical reaction as a cause of the splenic rupture. The patient underwent splenectomy and continuously received initial antituberculous drugs without change. To the best of our knowledge, this is the first report of spontaneous splenic rupture as a paradoxical reaction to antituberculous chemotherapy in an immunocompetent host with splenic TB.
Keywords
Tuberculosis; Tuberculosis, Splenic; Splenic Rupture; Disease Progression;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Peto HM, Pratt RH, Harrington TA, LoBue PA, Armstrong LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993-2006. Clin Infect Dis 2009;49:1350-7.   DOI
2 Sharma SK, Smith-Rohrberg D, Tahir M, Mohan A, Seith A. Radiological manifestations of splenic tuberculosis: a 23-patient case series from India. Indian J Med Res 2007;125:669-78.
3 Pramesh CS, Tamhankar AP, Rege SA, Shah SR. Splenic tuberculosis and HIV-1 infection. Lancet 2002;359:353.
4 Rathore S, George P, Deodhar M, Calton N, George U, Pawar B, et al. Spontaneous rupture of tuberculous spleen in a HIV seropositive patient on maintenance hemodialysis. Saudi J Kidney Dis Transpl 2009;20:822-5.
5 Lam KY, Ng WF, Chan AC. Miliary tuberculosis with splenic rupture: a fatal case with hemophagocytic syndrome and possible association with long standing sarcoidosis. Pathology 1994;26:493-6.   DOI
6 Ram R, Swarnalatha G, Prasad N, Murty KV. Pathological rupture of spleen in a haemodialysis patient due to tuberculosis. Nephrol Dial Transplant 2006;21:2994-5.   DOI
7 Weber E, Gunthard HF, Schertler T, Seebach JD. Spontaneous splenic rupture as manifestation of the immune reconstitution inflammatory syndrome in an HIV type 1 infected patient with tuberculosis. Infection 2009;37:163-5.   DOI
8 Rao RC, Ghose R, Sawhney S, Berry M. Hemangioma of spleen with spontaneous, extra-peritoneal rupture, with associated splenic tuberculosis: an unusual presentation. Australas Radiol 1993;37:100-1.   DOI
9 Safioleas MC, Stamatakos MC, Safioleas CM, Diab AI, Agapitos EB. Co-existence of spontaneous splenic rupture and tuberculosis of the spleen. Saudi Med J 2006;27:1588-90.
10 Fegan D, Butcher C, Rees C, Glennon J. Tuberculosis and abdominal pain. Intern Med J 2005;35:437-8.   DOI
11 Sterlacci W, Heiss S, Augustin F, Tzankov A. Splenic rupture, beyond and behind: a histological, morphometric and followup study of 254 cases. Pathobiology 2006;73:280-7.   DOI
12 Renzulli P, Hostettler A, Schoepfer AM, Gloor B, Candinas D. Systematic review of atraumatic splenic rupture. Br J Surg 2009;96:1114-21.   DOI
13 Park KY, Lee HJ, Jung JW, Choi YH, Nam SB, Ahn SH, et al. A case of different response of miliary lung and intracranial nodules to antituberculous therapy. Tuberc Respir Dis 2008;64:153-7.   DOI
14 Breen RA, Smith CJ, Bettinson H, Dart S, Bannister B, Johnson MA, et al. Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection. Thorax 2004;59:704-7.   DOI
15 Carvalho AC, De Iaco G, Saleri N, Pini A, Capone S, Manfrin M, et al. Paradoxical reaction during tuberculosis treatment in HIV-seronegative patients. Clin Infect Dis 2006;42:893-5.   DOI