| 1 |
Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med 2007; 13:567-9.
DOI
ScienceOn
|
| 2 |
Feghali-Bostwick CA, Gadgil AS, Otterbein LE, Pilewski JM, Stoner MW, Csizmadia E, et al. Autoantibodies in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008;177:156-63.
DOI
ScienceOn
|
| 3 |
Gadgil A, Zhu X, Sciurba FC, Duncan SR. Altered T-cell phenotypes in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006;3:487-8.
DOI
ScienceOn
|
| 4 |
Matzinger P. The danger model: a renewed sense of self. Science 2002;296:301-5.
DOI
ScienceOn
|
| 5 |
Parker LC, Prince LR, Sabroe I. Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity. Clin Exp Immunol 2007;147:199-207.
DOI
ScienceOn
|
| 6 |
Freeman CM, Curtis JL, Chensue SW. CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8＋ cells correlates with chronic obstructive pulmonary disease severity. Am J Pathol 2007;171:767-76.
DOI
ScienceOn
|
| 7 |
Bratke K, Klug M, Bier A, Julius P, Kuepper M, Virchow JC, et al. Function-associated surface molecules on airway dendritic cells in cigarette smokers. Am J Respir Cell Mol Biol 2008;38:655-60.
DOI
ScienceOn
|
| 8 |
Demedts IK, Bracke KR, Van Pottelberge G, Testelmans D, Verleden GM, Vermassen FE, et al. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007;175:998-1005.
DOI
ScienceOn
|
| 9 |
Di Stefano A, Caramori G, Capelli A, Gnemmi I, Ricciardolo FL, Oates T, et al. STAT4 activation in smokers and patients with chronic obstructive pulmonary disease. Eur Respir J 2004;24:78-85.
DOI
ScienceOn
|
| 10 |
Shapiro SD. End-stage chronic obstructive pulmonary disease: the cigarette is burned out but inflammation rages on. Am J Respir Crit Care Med 2001;164:339-40.
DOI
ScienceOn
|
| 11 |
Suga T, Kurabayashi M, Sando Y, Ohyama Y, Maeno T, Maeno Y, et al. Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life. Am J Respir Cell Mol Biol 2000;22:26-33.
DOI
ScienceOn
|
| 12 |
Voelkel N, Taraseviciene-Stewart L. Emphysema: an autoimmune vascular disease? Proc Am Thorac Soc 2005; 2:23-5.
DOI
ScienceOn
|
| 13 |
McDonald PP, Fadok VA, Bratton D, Henson PM. Transcriptional and translational regulation of inflaminflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol 1999;163:6164-72.
|
| 14 |
Wert SE, Yoshida M, LeVine AM, Ikegami M, Jones T, Ross GF, et al. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc Natl Acad Sci U S A 2000;97:5972-7.
DOI
ScienceOn
|
| 15 |
Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, et al. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol 2006;176:7657-65.
DOI
|
| 16 |
Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008; 177:861-70.
DOI
ScienceOn
|
| 17 |
Marwick JA, Caramori G, Stevenson CS, Casolari P, Jazrawi E, Barnes PJ, et al. Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice. Am J Respir Crit Care Med 2009;179:542-8.
DOI
|
| 18 |
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 2006; 127:1109-22.
DOI
ScienceOn
|
| 19 |
Sato T, Seyama K, Sato Y, Mori H, Souma S, Akiyoshi T, et al. Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking. Am J Respir Crit Care Med 2006;174:530-7.
DOI
ScienceOn
|
| 20 |
Vandivier RW, Fadok VA, Hoffmann PR, Bratton DL, Penvari C, Brown KK, et al. Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis. J Clin Invest 2002;109:661-70.
DOI
|
| 21 |
Ferrara F, D'Adda D, Falchi M, Dall'Asta L. The macrophagic activity of patients affected by pneumonia or chronic obstructive pulmonary disease. Int J Tissue React 1996;18:109-14.
|
| 22 |
Sauve AA, Wolberger C, Schramm VL, Boeke JD. The biochemistry of sirtuins. Annu Rev Biochem 2006;75: 435-65.
DOI
ScienceOn
|
| 23 |
Fujita M, Shannon JM, Irvin CG, Fagan KA, Cool C, Augustin A, et al. Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2001;280:L39-49.
|
| 24 |
Fraga MF, Agrelo R, Esteller M. Cross-talk between aging and cancer: the epigenetic language. Ann N Y Acad Sci 2007;1100:60-74.
DOI
ScienceOn
|
| 25 |
Boukamp P. Ageing mechanisms: the role of telomere loss. Clin Exp Dermatol 2001;26:562-5.
DOI
ScienceOn
|
| 26 |
Barnes PJ. Theophylline for COPD. Thorax 2006;61: 742-3.
DOI
ScienceOn
|
| 27 |
MacNee W. Oxidative stress and chronic obstructive pulmonary disease. Eur Respir Mon 2006;38:100-29.
|
| 28 |
Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 2006;28:219-42.
DOI
ScienceOn
|
| 29 |
Ito K, Ito M, Elliott WM, Cosio B, Caramori G, Kon OM, et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005;352:1967-76.
DOI
ScienceOn
|
| 30 |
Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proc Am Thorac Soc 2006;3:503-10.
DOI
ScienceOn
|
| 31 |
Lou Z, Chen J. Cellular senescence and DNA repair. Exp Cell Res 2006;312:2641-6.
DOI
ScienceOn
|
| 32 |
Rennard SI, Vestbo J. COPD: the dangerous underestimate of 15%. Lancet 2006;367:1216-9.
DOI
ScienceOn
|
| 33 |
Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med 2001;163:737-44.
DOI
ScienceOn
|
| 34 |
Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med 2009;360:2445-54.
DOI
ScienceOn
|
| 35 |
Henson PM, Cosgrove GP, Vandivier RW. State of the art. Apoptosis and cell homeostasis in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3:512-6.
DOI
ScienceOn
|
| 36 |
Vandivier RW, Henson PM, Douglas IS. Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease. Chest 2006;129:1673-82.
DOI
ScienceOn
|
| 37 |
Ito K, Barnes PJ. COPD as a disease of accelerated lung aging. Chest 2009;135:173-80.
DOI
ScienceOn
|
| 38 |
Honda Y, Takahashi H, Kuroki Y, Akino T, Abe S. Decreased contents of surfactant proteins A and D in BAL fluids of healthy smokers. Chest 1996;109:1006-9.
DOI
ScienceOn
|
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