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http://dx.doi.org/10.4046/trd.2010.68.1.29

A Case of Fatal Hyperinfective Strongyloidiasis with Acute Respiratory Failure and Intestinal Perforation in Lung Cancer Patient  

Kim, Hyeon-Sik (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Kim, Yu-Eun (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Yun, Eun-Young (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Ju, Ji-Hyun (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Ma, Jeong-Eun (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Lee, Gi-Dong (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Cho, Yu-Ji (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Kim, Ho-Cheol (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Lee, Jong-Deok (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Hwang, Young-Sil (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Jeong, Yi-Yeong (Department of Internal Medicine, Gyeongsang National University School of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.68, no.1, 2010 , pp. 29-33 More about this Journal
Abstract
Strongyloides stercoralis is an intestinal nematode that is a parasite to humans. The infecting filariform larvae of S. stercoralis enters the host body via the bloodstream, passes through the lungs, penetrates the alveoli, and then ascends the airway to transit down the esophagus into the small bowel. The infection can persist for decades without causing major symptoms and can elicit eosinophilia of varying magnitudes. Of note, this infection can also develop into a disseminated, often fatal, disease (hyperinfection) in patients receiving immunosuppressive corticosteroids. A 65-year-old man who was receiving corticosteroid therapy for the treatment of spinal stenosis was admitted to the emergency room with complaints of abdominal pain and severe dyspnea. We detected many S. stercoralis larvae in the sputum and in the bronchoalveolar-lavage sample collected by bronchoscopy. Here, we report a fatal case of strongyloidiasis with acute respiratory failure and intestinal perforation. In addition, we provide a brief review of the relevant medical literature.
Keywords
Strongyloides stercoralis; Respiratory Insufficiency; Intestinal Perforation; Immunosuppression;
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